Publication: Recurrent Pneumonias and Bronchiectasis - Is it an Immunodeficiency Disorder? - A Case Report
Date
2020
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Common Variable Immunodeficiency (CVID) is a form of primary immunodeficiency disorder characterised by hypogammaglobulinemia and recurrent sino-pulmonary infections. Its diagnosis is based on the presence of low serum IgG (< 2 SD below normal for age) with or without low IgA/ IgM levels and presentation beyond two years of age. These children also have disorders of autoimmunity with majority of them presenting as autoimmune cytopenias, predominantly thrombocytopenia and some having anaemia and neutropenias. Here we report a nine years old boy with past history of recurrent pneumonia, presenting this episode with fungal pneumonia, thrombocytopenia and anaemia eventually diagnosed as CVID.
Description
Sumit Agrawal
Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal
S Shreeram
Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal
A Jha
Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal
B Prajapati
Department of Paediatrics, Kanti Children’s Hospital, Maharajgunj, Kathmandu, Nepal
Keywords
Common variable immunodeficiency, cytopenias, fungal pneumonia, recurrent pneumonia