Publication: Drug - Receptor Interactions
Date
2011
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
In present-day pharmacology and medicine, it is usually taken for granted that
cells contain a host of highly specific receptors. Drugs act on the cell membrane by
physical and/or chemical interactions. This is usually through specific drug receptor
sites known to be located on the membrane. These are defined as proteins on or
within the cell that bind with specificity to particular drugs, chemical messenger
substances or hormones and mediate their effects on the body. Today, the
concept of specific receptors for drugs and transmitters lies at the very heart of
pharmacology. However, it is only relatively recently that the notion of drug-specific
receptors has become widely accepted, with considerable doubts being expressed
about their existence as late as the 1960s.
KEY WORDS
Drug, G-Protein, Interaction, PIP2, Receptor
Description
BS, Suvarna
Dept of Pharmacology, Melaka Manipal Medical College Manipal.