Publication: Pattern of Renal Cell Carcinoma – A Single Center Experience in Nepal
Date
2011
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Renal tumor is the 13th most common malignancy in the world and more than 90%
of renal tumors are renal cell carcinomas. As there is no data available on renal cell
carcinoma in Nepal, hence this study was undertaken to analyze the patterns of
renal cell carcinoma in patients with renal mass at a tertiary level hospital in Nepal.
Objectives
To analyze the patterns of renal cell carcinoma in patients with renal mass at a
tertiary level hospital in Nepal.
Methods
The case records of 50 consecutive patients with renal cell carcinoma presenting
at the Tribhuvan University Teaching Hospital, Kathmandu from July 2006 to June
2011 were retrospectively evaluated for presenting symptoms, physical finding,
investigation and histopathology report.
Results
Out of 50 patients, 64% were male and 36% were female. The age ranged between
11 to 78 years (mean ± SD: 55 ± 15 years). Fifty four percent of patients were
smokers. Incidentally tumor was detected in 40% cases by ultrasonography and
the typical triad was present in only 4%. The tumor was occupying upper pole in
40% of cases. The tumor size ranged from 3 to 15 cm (mean ± SD: 7.3 ± 2.9 cm).
Histopathologically, 76% of the patient had organ confined renal cell carcinoma (T1-
2 N0 M0). Clear cell was the most common type seen in 86%. Fuhrman’s nuclear
grade 2 was found in 50%.
Conclusion
Many of the renal cell carcinoma are detected incidentally, at an early stage and are
of clear cell subtype.
KEY WORDS
Incidental renal tumor, Nepal, Renal cell carcinoma.
Description
Sidharth, Luitel BR, Gupta DK, Maskey P, Chalise PR, Sharma UK, Gyawali PR, Shrestha GK, Sayami G, Joshi BR
Urology Unit Department of Surgery Tribhuwan University Teaching Hospital Maharajgunj, Kathmandu, Nepal.