Publication: Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Characteristics and Cycle Threshold Value (CT value) of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) of Nasopharyngeal Samples
| creativeworkseries.issn | ISSN 1990-7974 eISSN 1990-7982 | |
| dc.contributor.author | Kumar, Arvind | |
| dc.contributor.author | Arora, Harmeet Singh | |
| dc.contributor.author | Marwah, Vikas | |
| dc.contributor.author | Mishra, Satish Chandra | |
| dc.contributor.author | Ravi, Akhil K | |
| dc.contributor.author | Kalra, Dinesh Kumar | |
| dc.contributor.author | Shaw, Subhash Chandra | |
| dc.date.accessioned | 2025-11-02T08:37:36Z | |
| dc.date.available | 2025-11-02T08:37:36Z | |
| dc.date.issued | 2022 | |
| dc.description | Arvind Kumar Department of Respiratory and Sleep Medicine, Army Institute of Cardio-Thoracic Science, Pune-411040, Maharashtra, India Harmeet Singh Arora Department of Paediatrics, Army Hospital (Research and Referral), New Delhi-110010, India Vikas Marwah Department of Respiratory and Sleep Medicine, Army Institute of Cardio-Thoracic Science, Pune-411040, Maharashtra, India Satish Chandra Mishra Department of Cardiology, Army Institute of Cardio-Thoracic Science, Pune-411040, Maharashtra, India Akhil K Ravi Department of Respiratory and Sleep Medicine, Army Institute of Cardio-Thoracic Science, Pune-411040, Maharashtra, India Dinesh Kumar Kalra Department of Pathology, Command Hospital, Pune-411040, Maharashtra, India Subhash Chandra Shaw Department of Paediatrics, Army Hospital (Research and Referral), New Delhi-110010, India | |
| dc.description.abstract | Abstract: Introduction: We aimed to characterize epidemiological and clinical characteristics of children and adolescents with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, and to evaluate relationship of cycle threshold value (CT value) of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) test (As surrogate marker of viral load) with patient age and severity of infection. Methods: We retrospectively collected data of children and adolescents admitted in our center from April 2020 to July 2020 with positive RT-PCR test for SARS-CoV-2. Results: Total 62 children, with median (IQR) of age 96 (54 - 122) months and 39 adolescents with median (IQR) of age 19.5 (18.2 - 20) years were included. 56 (90%) children and 34 (87%) adolescents had history of SARSCoV-2 positive cases in their family. Only nine (14%) children had associated risk factor for severe SARS-CoV-2 infection. Fever was the commonest symptom which was present in 24 (39%) children and 16 (41%) adolescents. Cough was present in 17 (27%) children and 10 (26%) adolescents. Diarrhea was found in 14 (23%) children and three (8%) adolescents. CT values of RT-PCR test were similar in children and adolescence (p = 0.48). However, asymptomatic children had higher CT values than symptomatic children (p = 0.01). Conclusions: Majority of children have asymptomatic or mild SARS-CoV-2 infection with similar CT values in children and adolescents. | |
| dc.identifier | https://doi.org/10.3126/jnps.v42i2.41521 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/2997 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Paediatric Society (JNPS) | |
| dc.subject | COVID-19 | |
| dc.subject | Children | |
| dc.subject | Cycle Threshold Value | |
| dc.subject | RT-PCR test | |
| dc.subject | Vaccination | |
| dc.title | Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Characteristics and Cycle Threshold Value (CT value) of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) of Nasopharyngeal Samples | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 70 | |
| oaire.citation.startPage | 66 | |
| relation.isJournalIssueOfPublication | fdf27077-e090-4141-9c68-268731134932 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | fdf27077-e090-4141-9c68-268731134932 | |
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