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D-penicillamine Induced Myasthenia Gravis in Wilson’s Disease: A Case Report

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorThapa, Lekhjung
dc.contributor.authorThapa, Monika
dc.contributor.authorBhattarai, Suman
dc.contributor.authorShrestha, Abhishek Man
dc.contributor.authorSharma, Nooma
dc.contributor.authorRai, Nilshan
dc.contributor.authorPokharel, Merina
dc.contributor.authorPaudel, Raju
dc.date.accessioned2025-12-12T09:01:02Z
dc.date.available2025-12-12T09:01:02Z
dc.date.issued2022
dc.descriptionLekhjung Thapa Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Monika Thapa Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Suman Bhattarai Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Abhishek Man Shrestha Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Nooma Sharma Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Nilshan Rai KIST Medical College and Teaching Hospital, Imadol, Lalitpur, Nepal Merina Pokharel Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal Raju Paudel Department of Neurology, National Neuro Center, Maharajgunj, Chakrapath, Kathmandu, Nepal
dc.description.abstractAbstract Myasthenia gravis is a neuromuscular junction disorder characterised by fluctuating muscle weakness, improved by using anti-cholinesterase drugs. In addition to the autoimmune aetiology, various factors such as infections, surgery, and drugs are known to precipitate the condition. We report a case of a 15-year-old boy with D-penicillamine-induced myasthenia gravis who presented with facial diplegia, dysphagia, and drooling of saliva, 6 years after the initiation of treatment for Wilson’s disease. Therefore, clinicians should be more vigilant while prescribing patients with chelating drugs like D-penicillamine with regular monitoring of the new symptoms and keeping a very low threshold for the suspicion of myasthenia gravis.
dc.identifierhttps://doi.org/10.31729/jnma.7607
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3597
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectD-penicillamine
dc.subjectMyasthenia gravis
dc.subjectPyridostigmine
dc.subjectWilson's disease
dc.titleD-penicillamine Induced Myasthenia Gravis in Wilson’s Disease: A Case Report
dc.typeOther
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage647
oaire.citation.startPage644
relation.isJournalIssueOfPublication97a430e0-8e75-4ea0-8404-4f83f1f86a10
relation.isJournalIssueOfPublication.latestForDiscovery97a430e0-8e75-4ea0-8404-4f83f1f86a10
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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