Publication: Recent advances in the management of epilepsy: A review
Date
2005
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
Epilepsy is a complex disorder affecting brain function having a variety of contributing factors. The genetic
predisposition plays a key role in the genesis of epilepsy. The already existing antiepileptic drugs (AEDs) provide
effective control of majority of patents with different types of seizures. In some refractory cases and in those patients
who can not tolerate the conventional AEDs, there is an urgent need to provide relief by controlling the seizures
adequately. Various newer approaches in the rational management of seizures have been evolved during the recent
years, based on different mechanisms of action and side effects profile. A brief account of these newer treatment
modalities have been incorporated in this review in order to enlighten the readers about the possible beneficial effect
of this regimen vis a vis the limitations of such use.
Keywords: Neurotransmitter imbalance, defective gene, newer antiepileptic drugs, plasma levels, newer
approaches.