Publication: Hypokalemia Induced Partial Nephrogenic Diabetes Insipidus: A Case Report
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Diabetes insipidus is a condition characterised by a large volume of diluted urine production and increased thirst. In this case report, a 49-year-old gentleman presented with 3 months of polyuria and polydipsia. He had a repeated history of hypokalemia. On the evaluation of polyuria and polydipsia, he was diagnosed with partial nephrogenic diabetes insipidus based on his inability to concentrate urine after a water deprivation test and his less than 50% response to exogenous desmopressin. On the evaluation of recurrent hypokalemia, the investigation reports met biochemical criteria for the diagnosis of Gitelman syndrome. He was encouraged to increase his fluid intake as required, and potassium chloride supplementation relieved his symptoms. This case report demonstrates the reversibility of nephrogenic diabetes insipidus with a correction of hypokalemia.
Description
Anil Nepali
Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
Prakriti Adhikari
Kathmandu University School of Medical Sciences, Dhulikhel, Kavreplanchowk, Nepal.
Amit Shah
Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
Shailes Paudel
Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.
Prakriti Bhandari
Patan Academy of Health Sciences, Lagankhel, Lalitpur, Nepal.