Publication: Retinoblastoma in a 37 years old man in Nepal: A case report
Date
2010
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
Abstract
Retinoblastoma is extremely rare in adults. We report a case of Retinoblastoma diagnosed by histopathology in an
enucleated specimen of a 37 year old patient who presented with pain and diminished visual acuity with intraocular mass
and serous detachment. CT head and orbit showed uniform hyperdense mass in nasal quadrant of left globe projecting
into adjacent vitreous cavity. Chest X Ray and USG abdomen was unremarkable. Initially provisional diagnosis of
amelanotic melanoma was made. In view of nil visual prognoses enucleation was done. Sections from the enucleated
eyeball showed diffuse proliferation of tumour cells. These tumour cells were small sized with scanty cytoplasm, and
oval and hyper chromatic nuclei. A diagnosis of poorly differentiated Retinoblastoma was made with TNM (AJCC)
stage as T1NXMX.
This paper highlights the delayed presentation of retinoblastoma in adult. Although retinoblastoma is rare in adult,
we suggest keeping retinoblastoma in differential diagnosis of intraocular mass until proven histopathology report is
available.
Key words: Retinoblastoma, Adult, Intraocular mass
Description
Shrestha A 1, Adhikari RC 2, Saiju R 3
1 Tilganga Institute of Ophthalmology, Kathmandu, Nepal, 2Associate Professor, Consultant Pathologist, Tribhuvan University, Teaching Hospital, Kathmandu, Nepal, 3 Associate Professor, Consultant Oculoplatic Surgeon, Tilganga Institute of Ophthalmology, Kathmandu, Nepal