Transient Non-Ketotic Hyperglycinemia in a Newborn

Choudhury, Tarak; Kundu,Soumi; Das,  G.C.; Dasgupta, Malay Kumar

Publication:
Transient Non-Ketotic Hyperglycinemia in a Newborn

creativeworkseries.issn	ISSN 1990-7974 eISSN 1990-7982
dc.contributor.author	Choudhury, Tarak
dc.contributor.author	Kundu,Soumi
dc.contributor.author	Das, G.C.
dc.contributor.author	Dasgupta, Malay Kumar
dc.date.accessioned	2026-02-23T09:33:35Z
dc.date.available	2026-02-23T09:33:35Z
dc.date.issued	2016
dc.description	Tarak Choudhury RG Kar Medical College, Kolkata, West Bengal Soumi Kundu RG Kar Medical College, Kolkata, West Bengal G.C. Das RG Kar Medical College, Kolkata, West Bengal Malay Kumar Dasgupta RG Kar Medical College, Kolkata, West Bengal
dc.description.abstract	Abstract: In encephalopathic infants, cerebrospinal fluid hyperglycinemia and elevated cerebrospinal fluid to plasma glycine ratio are considered pathognomonic of Non-ketotic hyperglycinemia (NKH). It is due to a defect of the glycine cleavage system and has poor prognosis. We present a case of transient NKH presented to us with hypotonia, recurrent apnea and seizure. Increased ratio of cerebrospinal fluid to plasma glycine concentrations of 0.16 was seen as a strong diagnostic indicator of Non-ketotic hyperglycinemia.
dc.identifier	https://doi.org/10.3126/jnps.v36i3.16047
dc.identifier.uri	https://hdl.handle.net/20.500.14572/4876
dc.language.iso	en_US
dc.publisher	Nepal Paediatric Society (JNPS)
dc.subject	NKH
dc.subject	apnea
dc.subject	seizures
dc.subject	hypotonia
dc.subject	glycine
dc.subject	CSF
dc.subject	plasma
dc.title	Transient Non-Ketotic Hyperglycinemia in a Newborn
dc.type	Article
dspace.entity.type	Publication
local.article.type	Case Report
oaire.citation.endPage	306
oaire.citation.startPage	303
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