Publication: Lamotrigine Induced Severe Cutaneous Reaction
Date
2012
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Antiepileptic drugs are used commonly by physicians, neurologist and neurosurgeons in Nepal. Lamotrigine is an effective antiepileptic drug used as an add-on and monotherapy for a variety of seizure types in both adults and children. Rashes due to AED including SJS and hypersensitivity syndrome leading to hospitalization occur in approximately 0.33% of adults and 0.8% in children. Reactions due to LTG alone occur in around 5.7% of cases. We report probably the first case of this reaction in a 12-year old girl with a brief discussion on its etiology and management.
Description
YB Roka
Chief of Neurosurgery, Neuro Hospital, Biratnager
N Roka
Chief Ophthalmologist, Golcha Eye Hospital, Biratnagar
HB Adhikari
Medical Officer Neuro Hospital, Biratnagar
Keywords
AED, Epilepsy, Lamotrigine, Skin rash, Stevens-Johnson syndrome