Publication: Delayed Diagnosis of Pemphigus Vulgaris Initially Presenting as an Oral Ulcer: A Case Report
Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Pemphigus vulgaris is a rare autoimmune mucocutaneous blistering disease clinically presenting as vesicles, bullae, and erosion and histologically characterized by suprabasal split and acantholysis. It usually affects mucous membranes and skin. Recurrent oral ulcers can only be the clinical manifestation before progressing into skin lesions. This can lead to the delayed diagnosis of this disease. Here we report a case of pemphigus vulgaris which was diagnosed after years of suffering from an oral ulcer that eventually progressed to widespread skin blistering and ulceration. The patient was treated with oral prednisolone which showed improvement within a week. Physicians should consider the differential diagnosis of pemphigus vulgaris in patients presenting with a recurrent oral ulcer.
Description
Ramesh Lamichhane
Department of Internal Medicine, Jalalabad Ragib Rabeya Medical College, Pathantula, Sylhet, Bangladesh
Saroj Chaudhary
Department of Cardiology, Nepal Cardio Diabetes and Thyroid Center, Budhanilkantha, Kathmandu, Nepal
Keywords
Delayed diagnosis, Oral ulcer, Pemphigus vulgaris