Publication: Carcinosarcoma of the Cervix: A Case Report Authors
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Cervical carcinoma is the most common cause of mortality due to cancer in Nepal. Carcinosarcoma is a very rare subtype of cervical cancer which is characterized by the presence of both epithelial and mesenchymal malignant component. It constitutes less than 1% of cervical carcinoma. Due to the low occurrence of the disease, most of the data on treatment and prognosis are based on case reports and series. Here, we report a case of 69 years, female with cervical cancer (FIGO IIA2). Histopathological and immunohistochemical analysis of cervical biopsy initially showed primary adenosarcoma of the cervix. The tumor was non-responsive to primary treatment with concurrent chemoradiation. Later she was treated with abdominal hysterectomy and bilateral salpingo-oophorectomy. The final histopathology of the resected specimen showed a sarcomatous component along with carcinomatous changes in the endocervical glands favouring the diagnosis of carcinosarcoma of the cervix.
Description
Birendra Bhagat
Department of Gynecological Oncology, National Academy of Medical Sciences, Kathmandu, Nepal
Bijaya Chandra Aacharya
Department of Gynecological Oncology, B. P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Sarita Gurung
Department of Gynecological Oncology, B. P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Ranjan Raj Bhatta
3Department of Pathology, B. P. Koirala Memorial Cancer Hospital, Bharatpur, Nepal
Aasiya Rajbhandari
Department of Pathology, Paropkar Maternity and Women’s Hospital, Kathmandu, Nepal
Keywords
carcinosarcoma, cervix, sarcoma, surgery, treatment