Article:
Clinical and mycological profiling of superficial mycoses from tertiary care hospital in Nepal

creativeworkseries.issnOnline ISSN: 2676-1424; Print ISSN: 2676-1319
dc.contributor.authorSapkota, Jyotshna
dc.contributor.authorBhusal, Mohan
dc.contributor.authorAryal, Sachin K.
dc.contributor.authorKhadka, Shusila
dc.contributor.authorPandey, Ritu
dc.contributor.authorKhanal, Laxmi Kant
dc.contributor.authorAdhikari, Ram Prasad
dc.creator.affiliationDepartment of Microbiology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Dermatology, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.date.accessioned2026-10-07T09:36:33Z
dc.date.available2026-10-07T09:36:33Z
dc.date.issued2025
dc.description.abstractAbstract: Superficial mycoses are among the most common fungal infections worldwide, affecting the skin, hair and nails. Their prevalence and clinical profile can vary based on geographic, environmental, and host factors. This study aimed to determine the clinical and mycological profile of superficial mycoses among patients attending a tertiary care hospital. A cross-sectional study was conducted among 140 clinically diagnosed cases of superficial mycoses at Nepal Medical College Teaching Hospital. Detailed demographic and clinical data were recorded. Samples including skin scrapings, nail clippings, and plucked hairs were collected and subjected to direct KOH microscopy and fungal culture on Sabouraud dextrose agar and dermatophyte testing agar (DTM). Fungal isolates were identified based on colony morphology, lactophenol cotton blue mount and standard biochemical tests. Among 140 patients, 72 (51.42%) were male and 68 (48.58%) were female (male-to-female ratio 1.06:1). The most affected age group was 31– 40 years (27.86%). The most common clinical diagnoses were onychomycosis and Tinea corporis (24.28% each), followed by Tinea manuuam (14.29%). KOH microscopy was positive in 25.71% and culture in 15.71% of cases. Trichophyton spp. was the most frequently isolated fungus (54.54%), followed by Epidermophyton spp. (13.64%). Non-dermatophyte fungi such as Candida spp., Rhizopus spp., and Penicillium spp. were also identified. Superficial mycoses are common and often chronic, with varied clinical presentations. Trichophyton remains the predominant etiological agent, but non-dermatophyte fungi are emerging. Early diagnosis, accurate species identification, and appropriate treatment are essential to reduce disease burden and prevent recurrence.
dc.identifier.doihttps://doi.org/10.3126/nmcj.v27i3.84417
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8013
dc.language.isoen_US
dc.publisherNepal Medical College Pvt. Ltd.
dc.subjectDermatophytes
dc.subjectSuperficial mycoses
dc.subjectTinea
dc.subjectTrichophyton
dc.titleClinical and mycological profiling of superficial mycoses from tertiary care hospital in Nepal
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage171
oaire.citation.startPage165
relation.isJournalIssueOfPublicationc4da61e2-6075-40ce-abcf-fac83055d0e3
relation.isJournalIssueOfPublication.latestForDiscoveryc4da61e2-6075-40ce-abcf-fac83055d0e3
relation.isJournalOfPublication865934c8-5e95-468c-8ca6-7bb2529e4064

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