Publication:
Myocardial Infarction in Non-obstructive Coronary Arteries (MINOCA) in the Perioperative Period can Epinephrine be Responsible?

creativeworkseries.issn1812-2027
dc.contributor.authorKoirala, M
dc.contributor.authorShakya, BM
dc.contributor.authorParajuli, B
dc.contributor.authorGhimire, B
dc.date.accessioned2025-12-28T07:32:44Z
dc.date.available2025-12-28T07:32:44Z
dc.date.issued2022
dc.descriptionKoirala M,1 Shakya BM,1 Parajuli B,1 Ghimire B2 1Department of Anaesthesiology 2Department of Cardiothoracic and Vascular Anaesthesiology Tribhuvan University Teaching Hospital Institute of Medicine, Kathmandu, Nepal
dc.description.abstractABSTRACT Ephedrine, metaraminol, epinephrine and maneuvers like carotid sinus stimulation used during intraoperative period have been postulated to cause temporary spasm of the coronary vessels leading to decrease supply to the myocardium and precipitating myocardial infraction in non-obstructive coronary arteries (MINOCA). As an anaesthesiologists, we should be aware that even a dose as small as 25 mcg epinephrine infiltrated along with local anaesthetic in the subcutaneous plane may be responsible for coronary vessel spasm and thus myocardial infraction in non- obstructive coronary arteries. We report a case of 45 years old female with papillary carcinoma of thyroid who developed features of non-ST elevation myocardial infarction 5 minutes after the subcutaneous infiltration of 5 ml of 2% Xylocaine with 1:200000 Epinephrine. Patient was managed for acute Myocardial Infarction. Coronary angiogram done the next day revealed normal coronary arteries, hence the diagnosis Myocardial infraction in non-obstructive coronary arteries was made. KEY WORDS Acute myocardial infraction, Epinephrine, Local anaesthetics
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3918
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectAcute myocardial infraction
dc.subjectEpinephrine
dc.subjectLocal anaesthetics
dc.titleMyocardial Infarction in Non-obstructive Coronary Arteries (MINOCA) in the Perioperative Period can Epinephrine be Responsible?
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage537
oaire.citation.startPage535
relation.isJournalIssueOfPublicatione13d35fa-feec-42ac-b07f-e16ecf3ca759
relation.isJournalIssueOfPublication.latestForDiscoverye13d35fa-feec-42ac-b07f-e16ecf3ca759
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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