Publication: Dyschromatosis Universalis Hereditaria
Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Dyschromatosis universalis hereditaria (DUH) is a rare pigmentary genodermatosis
usually inherited in autosomal dominant fashion characterized by multiple pinpoint
to pea-sized hypo- and hyper-pigmented macules arranged in reticulate pattern that
develops within the first few years of life. An 11 years old boy presented with multiple
gradually progressive asymptomatic hypopigmented macules on hyperpigmented
background on trunk, extremities and face since 2 years of age. Family history was
absent. Punch biopsies revealed increased number of melanocytes in the epidermis
with basal cell vacuolar alteration and pigmentary incontinence and perivascular
infiltration by lymphocytes and melanophages in the dermis. We herein present a
sporadic case of dyschromatosis universalis hereditaria.
KEY WORDS
Dyschromatosis universalis hereditaria, Reticulate pigmentation
Description
Bista M,1 Agrawal S,1 Agrawal Y2
1Department of Dermatology and Venerology
2Department of Pathology
B.P. Koirala Institute of Health Sciences,
Dharan, Nepal
Keywords
Dyschromatosis universalis hereditaria, Reticulate pigmentation