Publication: Nosocomial Bacterial Infection and antimicrobial Resistant Pattern in a Tertiary care Hospital in Nepal
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Sah, MK | |
| dc.contributor.author | Mishra, SK | |
| dc.contributor.author | Ohora, H | |
| dc.contributor.author | Kirikae, T | |
| dc.contributor.author | Sherchan, JB | |
| dc.contributor.author | Rijal, BP | |
| dc.contributor.author | Pokhrel, BM | |
| dc.date.accessioned | 2026-05-06T06:42:31Z | |
| dc.date.available | 2026-05-06T06:42:31Z | |
| dc.date.issued | 2014 | |
| dc.description | MK Sah Department of Microbiology, Kathmandu University and 1 Kantipur Dental College, Teaching Hospital & Research Center, Kathmandu, Nepal SK Mishra Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal T Kirikae National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan JB Sherchan Department of Microbiology, Kathmandu University and 1 Kantipur Dental College, Teaching Hospital & Research Center, Kathmandu, Nepal BP Rijal Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal BM Pokhrel Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal | |
| dc.description.abstract | Abstract Introduction: Nosocomial infection is a global problem with multi facet outcomes. At present, the emergence of resistance to antimicrobial agents is a global public health problem which is well pronounced in developing countries. Methods: The aim of this study was to determine the prevalence of bacteria causing nosocomial infections and their antibiotics resistant pattern among the patients admitted at Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal. The study was conducted during a period of March 2011 to February 2012. Nine hundred clinical specimens which included urine, sputum, endotracheal aspirates, pus & blood were subjected for bacterial culture and their antibiotics sensitivity test at the Department of Microbiology with the use of standard method as described by American Society for Microbiology (ASM). Results: Prevalence of bacteria causing nosocomial infection was 34.4% (n=310). Out of 310 specimens, urine 122 (39.30%), sputum 78(25.2%), pus 78(25.2%), endotracheal secreation 24 (7.7%) and blood 8(2.6%). Three hundred thirty three bacteria were isolated from three hundred ten specimens. The most common isolates were Escherichia coli followed by Acinetobacter species, Klebsiella pneumonia and Staphylococcus aureus. In-vitro antibiotic susceptibility tests revealed that the Gram-negatives bacilli were only sensitive to fluroquinolones, ceftrixone, cefepime carbapenem, polymyxin B and colistin sulphate while the Gram-positive cocci were sensitive to fluroquinolones, Ceftroxone, cefepime and vancomycin. Conclusion: The findings suggested the need for constant monitoring of susceptibility of specific pathogens in different populations to commonly used anti-microbial agents to cope up this alarming situation in the hospital for the management of such patients and prevent the dissemination of such strains. Keywords: noscomical infections, bacteria and antibiotics | |
| dc.identifier | https://doi.org/10.59779/jiomnepal.567 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/6028 | |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Medicine | |
| dc.subject | noscomical infections | |
| dc.subject | bacteria and antibiotics | |
| dc.title | Nosocomial Bacterial Infection and antimicrobial Resistant Pattern in a Tertiary care Hospital in Nepal | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 48 | |
| oaire.citation.startPage | 38 | |
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