Publication:
Causes and Outcome of Neurogenic Vision Loss

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creativeworkseries.issn1999-6217
dc.contributor.authorGhimire, Pukar
dc.contributor.authorKarn, Ragesh
dc.contributor.authorGajurel, Bikram Prasad
dc.contributor.authorOjha, Rajeev
dc.contributor.authorRajbhandari, Reema
dc.contributor.authorShahi, Sumit
dc.contributor.authorPanthee, Pradeep
dc.contributor.authorBhandari, Pragya
dc.contributor.authorLamichhane, Jayaram
dc.date.accessioned2025-07-20T08:31:17Z
dc.date.available2025-07-20T08:31:17Z
dc.date.issued2024
dc.descriptionukar Ghimire Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal https://orcid.org/0000-0002-5834-2607 Ragesh Karn Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Bikram Prasad Gajurel Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Rajeev Ojha Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Reema Rajbhandari Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Sumit Shahi Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Pradeep Panthee Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Pragya Bhandari Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal Jayaram Lamichhane Department of Neurology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal
dc.description.abstractBackground: Neurogenic vision loss is often a medical emergency. Early evaluation and urgent treatment of the causes is the key to better visual prognosis. Methods: This was a retrospective cross-sectional study based on hospital records of patients admitted to the Neurology department of Tribhuvan University Teaching Hospital with complain of diminution of vision from April 2023 to March 2024. The visual outcome of the patients was recorded based on telephone interviews with the patients or their family members. Results: A total of 64 patients were identified of which 62 were interviewed for visual outcome. The median age was 38 years of which 62.5% were female. Bilateral eye involvement was reported in 59.4% of the cohort and half of the patients had normal optic disc. The distribution of visual acuity at presentation was 39.1% for 6/60 or better, 9.4% for 3/60 to less than 6/60, 32.8% for 3/60 and 18.8% having no perception of light. The commonest diagnosis in decreasing order of frequency was idiopathic intracranial hypertension, neuromyelitis optica spectrum disorder, idiopathic optic neuritis and myelin oligodendrocyte glycoprotein antibody disease with the frequency being 17.2%, 15.6%, 10.9% and 9.4% respectively. Of 62 patients interviewed, 67.7% reported a complete recovery of vision, 14.5% reported a partial recovery and 17.8% reported no visual recovery. Severity of visual loss at presentation was associated with poor visual outcome (p=0.021) whereas age, gender, number of eyes affected and duration of visual symptoms had no significant relation to visual recovery. Conclusions: Idiopathic intracranial hypertension, neuromyelitis optica spectrum disorder, Idiopathic optic neuritis, myelin oligodendrocyte glycoprotein antibody disease were the commonest causes of neurogenic visual loss. The severity of visual loss at onset is a prognostic marker of the visual recovery in these patients. Keywords: Blindness; Vision Disorders; Optic Nerve Diseases; Neural Optical Lesion
dc.identifierhttps://doi.org/10.33314/jnhrc.v22i03.5418
dc.identifier.urihttps://hdl.handle.net/20.500.14572/435
dc.language.isoen_US
dc.publisherNepal Health Research Council
dc.titleCauses and Outcome of Neurogenic Vision Loss
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage646
oaire.citation.startPage639
relation.isJournalIssueOfPublicationbdc38a4e-8fed-4c8d-ae10-a4918d68512e
relation.isJournalIssueOfPublication.latestForDiscoverybdc38a4e-8fed-4c8d-ae10-a4918d68512e
relation.isJournalOfPublication40bd2739-8b19-447c-be60-723a1bdd1dcd

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