Publication: Systemic Lupus Erythematosus Associated with Mixed-Type Autoimmune Hemolytic Anaemia and Vitamin B 12 Deficiency - A Case Report Authors
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Perinatal Society of Nepal (PESON)
Abstract
Abstract:
Systemic lupus erythematosus (SLE) is a chronic complex autoimmune disease. It generally presents with a wide spectrum of hematological and immunological abnormalities involving multiple systems. Autoimmune hemolytic anemia (AIHA) is a rare, acquired condition where the lifespan of red blood cells is shortened and very rarely associated with SLE. We report a 13 years old girl who presented to our emergency department with complaints of intermittent fever, generalized weakness, dizziness and rashes over the trunk and abdomen for three days. On examination, she was clinically stable and investigations revealed severe anemia, and deficiency of Vit –B12 along with SLE and Mixed AIHA. Chronic complex autoimmune diseases like SLE can rarely present as severe anemia with mixed AIHA and Vit B12 deficiency.
Description
Dipa Yadav
Department of Paediatric Intensive Care Unit, International Friendship Children’s Hospital, Maharajgunj, Kathmandu, Nepal.
Avinash Yadav
Department of Paediatric Intensive Care Unit, International Friendship Children’s Hospital, Maharajgunj, Kathmandu, Nepal.
Sushmita Bhandari
Shankarnagar Health Post, Department of Health Services, Rupandehi, Nepal.
Umesh Kumar Singh
Assistant Professor, Head of Department, Department of Paediatrics, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.
Keywords
Mixed autoimmune hemolytic anemia, pediatric, systemic lupus erythematosus, Vit- B12 deficiency.