Publication: Langerhans Cell Histiocytosis, presenting as Central Diabetes Insipidus and Pneumothorax a Case Report
Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Medicine
Abstract
Abstract
Langerhans cell histiocytosis (LCH) is a proliferative disorder where pathologic Langerhans cell accumulate in a various organ. We report a case of 28 years’ male who was admitted in medical ward for initial evaluation of pneumothorax and increased thirst. Laboratory workup revealed central diabetes insipidus. After careful examination, a skin lesion was found from which biopsy and immunophenotyping was performed that lead to the diagnosis of Langerhans cell histiocytosis with multisystem involvement. Patient was managed as per LCH protocol and intranasal desmopressin was prescribed for Diabetes Insipidus.
Keywords: Langerhans cell histiocytosis (LCH), Diabetes Insipidus, Pneumothorax
Description
V Pant
Resident Doctor, Department of Biochemistry
A Shrestha
Consultant Hematologist, Department of Medicine
S Baral
Lecturer, Endocrinology unit, Department of Medicine
B Bhattarai
Resident Doctor, Department of Biochemistry
U Bhatta
Resident Doctor. Department of Medicine
Keywords
Langerhans cell histiocytosis (LCH), Diabetes Insipidus, Pneumothorax