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A Cross-Sectional Study of Medication Adherence Pattern and Factors Affecting the Adherence in Chronic Obstructive Pulmonary Disease

creativeworkseries.issn1812-2027
dc.contributor.authorShrestha, R
dc.contributor.authorPant, A
dc.contributor.authorShakya Shrestha, S
dc.contributor.authorShrestha, B
dc.contributor.authorGurung, RB
dc.contributor.authorKarmacharya, BM
dc.date.accessioned2025-10-07T07:27:30Z
dc.date.available2025-10-07T07:27:30Z
dc.date.issued2015
dc.descriptionShrestha R,1,2 Pant A,1,3 Shakya Shrestha S,1,2 Shrestha B,1,3 Gurung RB,4 Karmacharya BM5 1Department of Pharmacology School of Medical Sciences, Kathmandu University 2Research & Development Division Dhulikhel Hospital, Kathmandu University Hospital 3Department of Human Biology Schools of Science & Medical Sciences Kathmandu University 4Department of Internal Medicine Dhulikhel Hospital, Kathmandu University Hospital 5Department of Community Program Dhulikhel Hospital, Kathmandu University Hospital
dc.description.abstractABSTRACT Background Chronic obstructive pulmonary disease (COPD) is considered as a major health problem, associated with mortality and morbidities. Various disease management strategies have been established to optimize patient’s longevity and functional status where patient adherence to the prescribed treatment plays a key role. Poor adherence to medication is common among COPD patients and is affected by number of factors like number of medicines, delivery devices and patient-related factors. Objective This study aims to investigate the adherence pattern in the management of COPD and factors affecting patient adherence to the prescribed treatment. Method This study is a cross-sectional study which was conducted in a tertiary care hospital. Those patients suffering from COPD of all age were enrolled in this study and prior informed consent was obtained from patients. The structured questionnaire was used to interview those patients. Result Total 100 patients were enrolled in this study, among which most patients (45%) were of age groups 60-70 years. Unintentional non-adherence to medication attributed for 65% of patients and the major reason was forgetfulness (52.3%). Most patients had discontinued the medication due to experience of side effects (63.3%). The result showed significant association between adherence and polypharmacy (p=0.00). However, there was no significant association between adherence and age, sex, mode of administration of drugs, technics to use delivery devices etc. Conclusion Majority of COPD patients were elderly (mean age= 68.4 years). Forgetfulness was associated with medication non-adherence. Most of the patients had discontinued medication because of side effects. Polypharmacy is one of the major factors associated with non-adherence to medication in COPD. KEY WORDS Adherence, COPD, Dhulikhel Hospital, non-adherence, polypharmacy
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2467
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectAdherence
dc.subjectCOPD
dc.subjectDhulikhel Hospital
dc.subjectNon-adherence
dc.subjectPolypharmacy
dc.titleA Cross-Sectional Study of Medication Adherence Pattern and Factors Affecting the Adherence in Chronic Obstructive Pulmonary Disease
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage70
oaire.citation.startPage64
relation.isJournalIssueOfPublicationde12cc8d-a515-472b-bb98-b9b70fdb6c7d
relation.isJournalIssueOfPublication.latestForDiscoveryde12cc8d-a515-472b-bb98-b9b70fdb6c7d
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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