Publication: Glue therapy for bleeding gastric varices: a single tertiary center experience in Nepal
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Jha, A | |
| dc.contributor.author | Sharma, S | |
| dc.contributor.author | Khadga, PK | |
| dc.contributor.author | Pathak, R | |
| dc.contributor.author | Poudyal, S | |
| dc.contributor.author | Hamal, R | |
| dc.date.accessioned | 2026-04-21T06:17:06Z | |
| dc.date.available | 2026-04-21T06:17:06Z | |
| dc.date.issued | 2017 | |
| dc.description | A Jha Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine S Sharma Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine PK Khadga Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine R Pathak Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine S Poudyal Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine R Hamal Department of Gastroenterology, Tribhuvan University Teaching Hospital, Institute of Medicine | |
| dc.description.abstract | Abstract Introduction: Bleeding is a common presentation in the Department of Gastroenterology, Institute of Medicine, Tribhuvan University Teaching Hospital. Of the varied causes of upper gastrointestinal bleed, bleeding gastric varices pose a major challenge to the endoscopist and the treating physician. Endoscopic injection of N-butyl-2-cyanoacrylate is the standard of care for treating gastric varices at present. Methods: We retrospectively evaluated the efficacy and safety of cyanoacrylate in patients presenting with gastric variceal bleed. Between May 2016 to April 2017, 25 patients (14-M, 11-F) who presented to Institute of Medicine, Tribhuvan University Teaching Hospital with gastric variceal bleeding underwent endoscopic treatment with N-butyl-2-cyanoacrylate. Results: Eleven patients had cirrhosis secondary to alcohol, 9 had non-cirrhotic portal hypertension, cirrhosis due to hepatitis B-1, hepatitis C-1, NASH-1, and cryptogenic- 2. Child-Pugh score at presentation for patients was Child A-52%, Child B-36% and Child C-12. Successful hemostasis. rebleeding rate and complications were reviewed. Immediate hemostasis was observed in 100 of the cases and carly rebleeding rate of 8% was seen in 2 patients. Complications included post procedure pain 16%, fever 16% and pulmonary embolism 4%. Conclusion: N-butyl-2-cyanoacrylate is an effective, lifesaving modality for immediate hemostasis of gastric variceal bleeding with an acceptable rebleeding rate. Keywords: N-butyl-2-cyanoacrylate, endoscopic injection, gastric variceal bleed | |
| dc.identifier | https://doi.org/10.59779/jiomnepal.943 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5833 | |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Medicine | |
| dc.subject | N-butyl-2-cyanoacrylate | |
| dc.subject | endoscopic injection | |
| dc.subject | gastric variceal bleed | |
| dc.title | Glue therapy for bleeding gastric varices: a single tertiary center experience in Nepal | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 83 | |
| oaire.citation.startPage | 80 | |
| relation.isJournalIssueOfPublication | 82bb8d43-dd4d-45eb-ab8b-524d98c77b9d | |
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