Publication: Acquired Epidermodysplasia Verruciformis Post-renal Transplant: A Case Report of Rare Manifestation of Immunosuppression
| creativeworkseries.issn | ISSN 2091-0231 eISSN 2091-167X | |
| dc.contributor.author | Neupane, Bidhan | |
| dc.contributor.author | Jwarchan, Jayanti | |
| dc.contributor.author | Adhikari, Bishnu Prasad | |
| dc.contributor.author | Kumar, Ajay | |
| dc.contributor.author | Sapkota, Surendra | |
| dc.contributor.author | Paudel, Subash | |
| dc.contributor.author | Oli, Ashmita | |
| dc.date.accessioned | 2025-10-10T08:58:36Z | |
| dc.date.available | 2025-10-10T08:58:36Z | |
| dc.date.issued | 2025 | |
| dc.description | Author Biographies Bidhan Neupane, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Jayanti Jwarchan, Manipal College of Medical Sciences, Pokhara, Nepal Lecturer, Department of Dermatology,Manipal College of Medical Sciences, Pokhara, Nepal Bishnu Prasad Adhikari, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Ajay Kumar, Manipal College of Medical Sciences, Pokhara, Nepal Professor, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Surendra Sapkota, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology,Manipal College of Medical Sciences, Pokhara, Nepal Subash Paudel, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal Ashmita Oli, Tribhuvan University Institute of Medicine, Maharajgunj Nursing Campus Adult Health Nursing, Maharajgunj Nursing Campus, Tribhuvan University, Institute of Medicine, Kathmandu, Nepal. | |
| dc.description.abstract | Abstract: Acquired epidermodysplasia verruciformis (EV) is a rare dermatologic disorder linked to increased susceptibility to specific HPV infections in immunosuppressed states. We report a 43-year-old renal transplant recipient on prolonged immunosuppressive therapy with tacrolimus, mycophenolate mofetil, and corticosteroids who developed multiple asymptomatic wart-like papules and plaques on extremities, hypopigmented pityriasis versicolor-like macules on the trunk, and seborrheic keratosis-like lesions on the face. Histopathology confirmed EV, showing acanthosis, hyperkeratosis, and keratinocytes with pale blue cytoplasm, perinuclear halos, and mild nuclear dysplastic changes. Due to malignancy risk in sun-exposed areas, strict sun protection and follow-up were advised. With acitretin and imiquimod unavailable, lesions were managed with intralesional measles, mumps, rubella (MMR) vaccine, and topical keratolytic, resulting in partial regression. This case highlights the need for early recognition, vigilant monitoring, and tailored management of EV in immunosuppressed patients, emphasizing further research to refine therapeutic strategies in resource-limited settings. | |
| dc.identifier | https://doi.org/10.3126/njdvl.v23i1.74640 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/2565 | |
| dc.language.iso | en_US | |
| dc.publisher | Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) | |
| dc.title | Acquired Epidermodysplasia Verruciformis Post-renal Transplant: A Case Report of Rare Manifestation of Immunosuppression | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Case Report | |
| oaire.citation.endPage | 59 | |
| oaire.citation.startPage | 55 | |
| relation.isJournalIssueOfPublication | e8242928-66a2-470a-8f53-47365c4dd836 | |
| relation.isJournalIssueOfPublication.latestForDiscovery | e8242928-66a2-470a-8f53-47365c4dd836 | |
| relation.isJournalOfPublication | b2ab7aab-75b0-4bd1-9ed0-b8a91c68201a |