Publication: Behcet’s Disease with Absent HLA Serotyping and Pathergy Test
Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Behcet’s disease is a multisystemic vasculitis of unknown etiopathogenesis
characterized by recurrent acute inflammation. A 30-year male presented with
progressive blurred vision in both eye for one month associated with photophobia,
redness and ocular pain. On presentation best corrected visual acuity was 6/9 both
eyes. Bilateral ocular examination of anterior segment demonstrated occasional
cells. Treatment history of multiple joint pain along with oral aphthous ulcers.
Erythematous papulopustular lesion over face, neck, trunk and genital ulcers were
being treated. Irrespective of negative human leucocyte antigen B51 and pathergy,
patient was diagnosed as Behcet’s disease on the basis of clinical criteria and
started with topical steroid and cycloplegic. At one-month, ocular symptoms were
relieved. Behcet’s disease is a rare, autoimmune disease, which lacks universal
pathognomonic test and investigations, therefore diagnosis is primarily done with
international criteria for Behcet’s disease. Multidisciplinary approach certainly
helps in early diagnosis and eliminating morbidity.
KEY WORDS
Behcet’s disease, HLAB51, Pathergy test, Silk road, Uveitis
Description
Ranabhat S,1 Byanju R,1 Khadka S2
1Department of Vitreo-retina
Bharatpur Eye Hospital
Bharatpur, Chitwan, Nepal
2Department of Vitreo-retina
Nepal Eye Hospital
Kathmandu, Nepal
Keywords
Behcet’s disease, HLAB51, Pathergy test, Silk road, Uveitis