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Epithelioid Gastrointestinal Stromal Tumor of Duodenum Mimicking Adenocarcinoma: A Case Report Authors

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorTiwari, Sansar Babu
dc.contributor.authorKarki, Shovana
dc.date.accessioned2026-02-12T05:16:55Z
dc.date.available2026-02-12T05:16:55Z
dc.date.issued2021
dc.descriptionSansar Babu Tiwari Department of Pathology, Mahajargunj Medical Campus, Kathmandu, Nepal https://orcid.org/0000-0002-6900-9383 Shovana Karki Department of Pathology, Mahajargunj Medical Campus, Kathmandu, Nepal https://orcid.org/0000-0001-5429-2422
dc.description.abstractAbstract: Gastrointestinal stromal tumor is a mesenchymal tumor of gastro-intestinal tract. This epithelioid type gastrointestinal stromal tumor seen in a 22-year-old male with epigastric pain as a presenting symptom had morphological resemblance to carcinoma. However, the immunohistochemistry profile with CD117 and DOG 1 positivity, combined with AE1/AE3 positivity confirmed the tumor as gastrointestinal stromal tumor. Approximately 95% of the patients with gastrointestinal stromal tumor show CD117 immunoreactivity. The treatment approach of CD117 positivity in gastrointestinal stromal tumor has therapeutic benefit with tyrosine kinase inhibitors. Preoperative Imatinib therapy with complete excision can decrease the disease recurrence. Histopathological examination with immunohistochemical studies help to reach the definite diagnosis.
dc.identifierhttps://doi.org/10.31729/jnma.6104
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4709
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectepithelioid
dc.subjectskeinoid fibres
dc.subjecttyrosine kinase
dc.titleEpithelioid Gastrointestinal Stromal Tumor of Duodenum Mimicking Adenocarcinoma: A Case Report Authors
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage1312
oaire.citation.startPage1310
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relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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