Publication: Herlyn Werner Wunderlich Syndrome Presenting with Ischemic Stroke due to Suspected Paroxysmal Nocturnal Hemoglobinuria: A Case Report
Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract:
Paroxysmal nocturnal hemoglobinuria can rarely present as cerebral ischemia and stroke due to arterial thrombosis. However, it should be considered in a young patient with bone marrow failure features, systemic thromboses, and hemolysis. The variants of paroxysmal nocturnal hemoglobinuria pose a diagnostic challenge and hence are important to recognize. We report a case of a 28-years-old female with Herlyn Werner Wunderlich Syndrome who presented with an ischemic cerebrovascular accident, pancytopenia, hemoglobinuria, and widespread abdominal thromboses suggestive of paroxysmal nocturnal hemoglobinuria. The patient was managed symptomatically and referred to a hematologist.
Description
Ayushma Acharya
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
https://orcid.org/0000-0002-4955-2397
Prajwala Yogi
Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Pramod Singh
Faisalabad Medical University, Punjab, Pakistan
https://orcid.org/0000-0001-6350-6293
Tulsi Ram Bhattarai
Department of Internal Medicine, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal
Keywords
cerebral ischemia, aroxysmal nocturnal hemoglobinuria, stroke