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Azathioprine Induced Pancytopenia in a Patient with Vogt-Koyanagi-Harada Disease: A Case Report

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorKhatri, Sagun
dc.contributor.authorKhatri, Saugat
dc.contributor.authorRegmi, Sachit
dc.contributor.authorPyakurel, Sulav
dc.contributor.authorBhattarai, Sanjeet
dc.contributor.authorBarman, Pankaj
dc.contributor.authorManandhar, Dilasha
dc.contributor.authorSingh, Abhi Kumar
dc.date.accessioned2025-11-11T07:04:40Z
dc.date.available2025-11-11T07:04:40Z
dc.date.issued2022
dc.descriptionSagun Khatri B.P. Koirala Institute of Health Sciences, Dharan, Sunsari, Nepal Saugat Khatri Nepal Mediciti, Nakhkhu Patan, Lalitpur, Nepal Sachit Regmi Nepal Mediciti, Nakhkhu Patan, Lalitpur, Nepal Sulav Pyakurel Nepal Mediciti, Nakhkhu Patan, Lalitpur, Nepal Sanjeet Bhattarai Nepal Mediciti, Nakhkhu Patan, Lalitpur, Nepal Pankaj Barman Nepal Mediciti, Nakhkhu Patan, Lalitpur, Nepal Dilasha Manandhar Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal Abhi Kumar Singh Postgraduate Institute of Medical Education and Research, Madhya Marg, Chandigarh, India
dc.description.abstractAbstract Vogt-Koyanagi-Harada disease is a multisystem autoimmune inflammatory disorder that affects the eyes, ears, skin, and the nervous system. It is a rare disease that mainly affects Asian, Hispanic, and Middle Eastern populations. Systemic steroids and immunosuppressants are frequently used to treat autoimmune diseases like this. Despite the fact that they reduce morbidity, immunosuppressants can have a number of side effects and are difficult to use, particularly when treating uncommon autoimmune illnesses. We present a case of a 56-year-old man who visited our health facility complaining of increased tears in both eyes along with bilateral blurring of vision. He was subsequently identified as having Vogt-Koyanagi-Harada disease. After prednisolone and methotrexate failed to have the desired effect, he was treated with azathioprine, which caused pancytopenia, and manifested as fever with positive blood culture for a coagulase-negative staphylococcus infection.
dc.identifierhttps://doi.org/10.31729/jnma.7867
dc.identifier.urihttps://hdl.handle.net/20.500.14572/3112
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectCase reports
dc.subjectPancytopenia
dc.subjectSteroid
dc.titleAzathioprine Induced Pancytopenia in a Patient with Vogt-Koyanagi-Harada Disease: A Case Report
dc.typeOther
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage905
oaire.citation.startPage902
relation.isJournalIssueOfPublication3668fd65-4a8c-4e92-a7cc-aa6ea7518d82
relation.isJournalIssueOfPublication.latestForDiscovery3668fd65-4a8c-4e92-a7cc-aa6ea7518d82
relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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