Publication: Prevalence of peripheral arterial disease by ankle-brachial index and its correlation with carotid intimal thickness and coronary risk factors in Nepalese population over the age of forty years
Files
Date
2007
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
Objectives: Noninvasive measures of subclinical atherosclerosis such as the ankle brachial index (ABI) and
common carotid artery intima-media thickness (CCA IMT) could improve risk prediction and provide more focused
primary prevention strategies. This report describes the prevalence of subclinical atherosclerotic vascular disease in
a Nepalese population over the age of forty years as measured by ABI and CCA IMT and their association with
established cardiovascular risk factors.
Materials and methods: Ultrasonic evaluation of ABI and CCA IMT was done in 195 individuals of age 40 years
and above who had presented to an outpatient department. Patients with established diagnosis of coronary artery
disease or symptomatic for peripheral arterial disease were excluded from the study.
Results: The prevalence of atherosclerotic disease as measured by ABI was 18.5% and there was a statistically
significant correlation between ABI and CCA IMT and other established cardiovascular risk factors such as
smoking, diabetes mellitus and hypertension.
Conclusions: We recommend that ABI as measured by sphygmomanometer be incorporated into routine
cardiovascular screening and when found to be abnormal further confirmed by Doppler assessment of ABI and CCA
IMT as surrogate markers of atherosclerotic vascular disease.
Key words: atherosclerosis, cardiovascular disease, peripheral vascular disease, carotid arteries
Description
Sodhi HS 1 , Shrestha SK 2, Rauniyar R 3, Rawat B4
1Head, Department of Non-invasive Cardiology, Norvic Escorts International Hospital, 2Emergency In charge,Norvic Escorts International Hospital, 3
Executive director, Life Care Hospital, 4Executive director, Norvic Escorts
International Hospital