Publication: Clinico-pathological Spectrum of Oral Cavity Lesions at a Tertiary Care Center in Central Nepal: A Descriptive Cross-sectional Study
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Bastakoti, Shankar | |
| dc.contributor.author | Shrestha, Gambhir | |
| dc.contributor.author | Gautam, Dej Kumar | |
| dc.contributor.author | Dhungana, Ishan | |
| dc.contributor.author | Jha, Nandita | |
| dc.contributor.author | Pandey, Greta | |
| dc.contributor.author | Upreti, Suraj | |
| dc.contributor.author | Shrestha, Ashmita | |
| dc.contributor.author | Bhatta, Ranjan Raj | |
| dc.date.accessioned | 2026-03-13T06:58:36Z | |
| dc.date.available | 2026-03-13T06:58:36Z | |
| dc.date.issued | 2021 | |
| dc.description | Shankar Bastakoti Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal https://orcid.org/0000-0002-0446-1440 Gambhir Shrestha Department of Cancer Prevention, Control and Research, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Dej Kumar Gautam Department of Surgical Oncology, ENT, Head and Neck Unit, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Ishan Dhungana Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Nandita Jha Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Greta Pandey Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Suraj Upreti Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal Ashmita Shrestha Department of Pathology, Universal College of Medical Sciences, Bhairahawa, Nepal Ranjan Raj Bhatta Department of Pathology, BP Koirala Memorial Cancer Hospital, Chitwan, Nepal | |
| dc.description.abstract | Abstract: Introduction: Head and neck cancer is the sixth most common cancer in the world. The disease burden is increasing at an alarming rate in developing Southeast Asian countries. This study aims to report the histopathological spectrum of oral cavity lesions at a tertiary cancer center in central Nepal. Methods: This study included all those cases of oral cavity lesions, of which diagnostic biopsy was done from January 2018 to December 2019. The data were retrieved from the Department of Pathology of BP Koirala Memorial Cancer Hospital. The study proposal was approved by the Institutional Review Committee at BPKMCH (Ref: 247/2020) on 28th June 2020. Convenience sampling was done. Data was analyzed using Statistical Package for the Social Sciences version 20 using descriptive statistics. Results: A total of 851 cases of oral cavity lesions were included in this study. The mean age of the study population was 55.9 years, with male to female ratio of 3:1. Malignant lesions composed of 472 (55.5%) cases followed by premalignant lesion of 104 (12%). More than 453 (95%) malignant cases were squamous cell carcinoma, of which 342 (75%) were a well-differentiated type. The buccal cavity is the most common site of malignant lesion 212 (45%), followed by tongue 96 (20%) and lower gingivobuccal region 86 (18%). Conclusions: Malignant lesions are the most common histopathological findings in the oral cavity lesion with squamous cell carcinoma type. Oral cancer is common cancer that can be prevented and cured if detected early. | |
| dc.identifier | https://doi.org/10.31729/jnma.5539 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5109 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | oral cancer | |
| dc.subject | squamous cell carcinoma | |
| dc.subject | tobacco | |
| dc.title | Clinico-pathological Spectrum of Oral Cavity Lesions at a Tertiary Care Center in Central Nepal: A Descriptive Cross-sectional Study | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 127 | |
| oaire.citation.startPage | 124 | |
| relation.isJournalIssueOfPublication | f3e5af8c-a6f3-4c94-b589-d2f335a6924c | |
| relation.isJournalIssueOfPublication.latestForDiscovery | f3e5af8c-a6f3-4c94-b589-d2f335a6924c | |
| relation.isJournalOfPublication | e6e146a0-0ece-4aba-aa0a-6ccfbd10a12a |