Publication: Raised D-dimer among Admitted COVID-19 Patients in a Tertiary Care Centre: A Descriptive Cross-sectional Study
Date
2022
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Patients with COVID-19 are characterised by abnormal levels of inflammatory biomarkers. Elevated D-dimer in COVID-19 patients is associated with increased mortality. This study aimed to find out the prevalence of raised D-dimer among COVID-19 patients in a tertiary care centre.
Methods: This descriptive cross-sectional study was conducted in COVID-19 unit of a tertiary care centre from 23 January 2021 to 19 June 2021. The ethical approval was taken from the Institutional Review Committee (Reference number: 077/078/159). D-dimer values and demographic data of the hospital-admitted COVID-19 patients were recorded. Convenience sampling technique was used. Point estimate and 95% Confidence Interval were calculated.
Results: Out of 180 patients with COVID-19 admitted in the hospital, the D-dimer levels were raised in 85 (47.22%) (39.93-54.51, 95% Confidence Interval) patients.
Conclusions: The prevalence of raised D-dimer among admitted COVID-19 patients was found to be lower when compared to other studies conducted in similar settings.
Description
Dipesh Karki
Department of Medicine, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal
Roshani Gurung
Pharmacy Programme, Gandaki University, Pokhara, Kaski, Nepal
Prasanna Nepali
Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal
Hari Prasad Kaphle
School of Health and Allied Sciences, Pokhara University, Pokhara, Kaski, Nepal
Bhabuk Subedi
Department of Intensive Care Unit, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal
Sundar Adhikari
Department of Pharmacy, Fishtail Hospital and Research Center Private Limited, Pokhara, Kaski, Nepal
Keywords
COVID-19, D-dimer, Nepal, Prevalence