Publication: Pseudohypoparathyroidism as a Cause of Refractory Seizures
Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Pseudohypoparathyroidism is a genetic disorder that is similar to hypoparathyroidism, but which results from the body’s lack of response to parathyroid hormone rather than its decreased production. Serum level of immunoreactive Parathormone are elevated instead. We report a four month old infant in status epilepticus associated with hypocalcemia, hyperphosphatemia and raised parathyroid hormone level. Hypocalcemia was resistant to calcium therapy initially but responded to vitamin D analogue therapy leading to diagnosis of Pseudohypoparathyroidism.
Description
Gurmeet Singh
MBBS, MD, Associate Professor, Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research
Karuna Thapar
MBBS, MD, Professor, Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research
Preeti Malhotra
MBBS, MD Associate Professor, Department of Paediatrics, Sri Guru Ram Das Institute of Medical Sciences and Research
Keywords
Hypocalcemia, Seizures, Pseudohypoparathyroidism