Article: Multidisciplinary cooperation in a simultaneous combined liver and kidney transplantation patient of primary hyperoxaluria 1
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Qingqi, Ren | |
| dc.contributor.author | Weiqiang, Ju | |
| dc.contributor.author | Dongping, Wang | |
| dc.contributor.author | Zhiyong, Guo | |
| dc.contributor.author | Maogen, Chen | |
| dc.contributor.author | Xiaoshun, He | |
| dc.creator.affiliation | Department of hepatobiliary and pancreatic surgery, Peking University Shenzhen Hospital, Shenzhen China. | |
| dc.creator.affiliation | Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. | |
| dc.creator.affiliation | Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. | |
| dc.creator.affiliation | Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. | |
| dc.creator.affiliation | Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. | |
| dc.creator.affiliation | Organ Transplant Center, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China. | |
| dc.date.accessioned | 2026-09-22T06:45:47Z | |
| dc.date.available | 2026-09-22T06:45:47Z | |
| dc.date.issued | 2017 | |
| dc.description.abstract | Abstract Primary hyperoxaluria type 1 is an autosomal recessive hereditary glyoxylate metabolism disorder characterized by excessive production of oxalate, caused by the deficiency of liver specific peroxisomal enzyme: alanineglyoxylate aminotransferase. For patients with end-stage renal disease, combined liver and kidney transplantation was needed. This report describes one patient, with a diagnosis of end-stage renal disease and primary hyperoxaluria 1 confirmed by PCR and direct sequencing with genomic DNA, received the simultaneous combined liver and kidney transplantation after seven months’ waiting. However, there were several complications observed post surgery, such as protracted bleeding, common bile duct anastomotic stenosis, biliary calculi and recurrence of urolithiasis. All these were well solved by relevant department, and finally a satisfactory outcome was achieved. Multidisciplinary cooperation plays an important role on the PH1 patient management, especially when multiple complications are encountered. Keywords: Primary hyperoxaluria type 1; End-stage renal disease; Liver transplantation; Kidney transplantation. | |
| dc.identifier.doi | https://doi.org/10.31729/jnma.2671 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/7806 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.subject | Primary hyperoxaluria type 1 | |
| dc.subject | End-stage renal disease | |
| dc.subject | Liver transplantation | |
| dc.subject | Kidney transplantation | |
| dc.title | Multidisciplinary cooperation in a simultaneous combined liver and kidney transplantation patient of primary hyperoxaluria 1 | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Case Report | |
| oaire.citation.endPage | 178 | |
| oaire.citation.startPage | 175 | |
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