Publication: A comparison of haemodynamic responses with pethidine vs. butorphanol in open cholecystectomy cases
Date
2004
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
Objective: The present study was undertaken to compare the haemodynamic responses with pethidine vs.
Butorphanol intraoperatively in open cholecystectomy cases in KMCTH.
Method: In this randomized study, all together 40 patients undergoing routine cholecystectomy surgery were
included. Group A received Pethidine 1mg/kg and Group B received Butorphanol 0.04mg/kg intraoperatively. Heart
rate and blood pressure were recorded before injection of the drug, after injection, before intubation, after intubation,
before skin incision, after incision, before extubation and after extubation Data analysis was done using independent
sample “t” test.
Result: Our study showed no statistical significance in haemodynamic responses with either pethidine or
Butorphanol in open cholecystectomy cases.
Conclusion: Both drugs appear equally good analgesics in our study.
Key words: analgesics, pethidine, Butorphanol, haemodynamic responses, surgery, cholecystectomy.