Article:
Effect of nebulized lignocaine on prevention of postoperative sore throat following laparoscopic cholecystectomy

creativeworkseries.issnOnline ISSN: 2676-1424; Print ISSN: 2676-1319
dc.contributor.authorBajracharya, Ashis Ratna
dc.contributor.authorBajracharya, Gautam Ratna
dc.contributor.authorThapa, Chitra
dc.contributor.authorBhandari, Sabin
dc.creator.affiliationDepartment of Anesthesia, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Anesthesia, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Anesthesia, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.creator.affiliationDepartment of Anesthesia, Nepal Medical College and Teaching Hospital, Attarkhel, Gokarneshwor-8, Kathmandu
dc.date.accessioned2026-10-27T10:12:41Z
dc.date.available2026-10-27T10:12:41Z
dc.date.issued2024
dc.description.abstractAbstract: Post-operative sore throat (POST) is one of the common side effects of general anesthesia with endotracheal intubation. Several medications have been tried for the prevention of POST. Nebulized lignocaine is easily available, easily administered, cost-effective, and acts immediately with a short duration of action and minimal systemic effects with no long-term residual effects. We conducted this study to find the prevalence of POST when preoperative nebulization with 2% lignocaine is used in patients following laparoscopic cholecystectomy. We also studied the factors associated with POST. This study was done in 100 patients who underwent laparoscopic cholecystectomy and received preoperative lignocaine nebulization. The incidence of POST was measured at 0, 6, 12, and 24 hours postoperatively and various risk factors that might have predisposed for the development of POST were also studied. The mean age of the patients was 42.53±12.82 years. A total of 40 patients (40.0%) experienced POST at any time point during the study period. The majority of patients had mild i.e. Grade 1 POST (11-21%). Patients with a BMI > 30 kg/m2, CL grade 4, high cuff volume, airway trauma, higher duration of intubation, and higher pneumoperitoneum duration had a greater incidence of POST at all post-operative periods. We concluded that nebulization of 5 ml of 2.0% lignocaine decreases the intensity and treatment requirement for POST and has minimal side effects. A higher incidence of POST is seen in patients who had a higher CL grading, higher BMI, high cuff volume, airway trauma, higher duration of intubation, and longer pneumoperitoneum duration.
dc.identifier.doihttps://doi.org/10.3126/nmcj.v26i2.67206
dc.identifier.urihttps://hdl.handle.net/20.500.14572/8181
dc.language.isoen_US
dc.publisherNepal Medical College Pvt. Ltd.
dc.subjectLaparoscopic cholecystectomy
dc.subjectlignocaine
dc.subjectnebulization
dc.subjectpost-operative sore throat
dc.titleEffect of nebulized lignocaine on prevention of postoperative sore throat following laparoscopic cholecystectomy
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage143
oaire.citation.startPage138
relation.isJournalIssueOfPublication84c0efe2-3683-4d69-82dc-de66f7d150e3
relation.isJournalIssueOfPublication.latestForDiscovery84c0efe2-3683-4d69-82dc-de66f7d150e3
relation.isJournalOfPublication865934c8-5e95-468c-8ca6-7bb2529e4064

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