Publication: Antibacterial activities of locally used toothpastes againstdental pathogens
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Date
2008
Article Type
Original Article
Journal Title
Journal ISSN
ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987
Volume Title
Pages
Pages: 15 - 18
Publisher
Institute of Medicine
Abstract
Abstract
Background: Toothpastes need to contain various antimicrobial agents in order to reduce, control and prevent different kinds of dental diseases. Different brands have their own composition and concentration of ingredients for their efficacy. The consumers should aware about the facts associated with their health.
Methods: The bacterial pathogens were isolated and identified from various dental samples. Antibacterial activities of 11 different toothpastes available locally in markets were assessed against the isolates by standard agar well diffusion method.
Result: Monomicrobial infections were observed in all cases. The bacterial pathogens were found to be Streptococcus mutans, S. salivarius, S. sanguis, S. sobrinus and S. mitis. Of the assayed toothpastes- Colgate Total, Colgate, Anchor White and Pepsodont were found to be highly effective against the pathogens.
Conclusion: The result showed that the toothpastes containing Triclosan as a major chemical ingredient posses significant antibacterial activities.
Keywords: Streptococcus, Triclosan, Zone-of-inhibition
Description
K.B Tiwari
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
U.T. Shrestha
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
A. Acharya
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
B. Subedi
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
B. Paudyal
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
M. Jnawali
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
p. SAKYA
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
U. KC
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
V.P Agrawal
Central Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal, Research Laboratory for Agricultural Biotechnology and Biochemistry (RLABB), Maitidevi, Kathmandu, Nepal
Keywords
Streptococcus, Triclosan, Zone-of-inhibition
Identifier
https://doi.org/10.59779/jiomnepal.344