Publication: Prevalence and Risk Factors of Osteoporosis among Postmenopausal Women Visiting a District Hospital of Nepal: An Observational Study
Date
2024
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Medical Association
Abstract
Abstract
Introduction: Osteoporosis and low bone mass affect millions of people worldwide, leading to severe consequences ranging from disability to mortality. This study aimed to determine the prevalence and risk factors of osteoporosis among postmenopausal women in a district of Nepal.
Methods: An analytical cross-sectional study involving postmenopausal women from Nuwakot, Dhading, and Rasuwa districts in Nepal was conducted at Trishuli Hospital, Nuwakot. Ethical approval was taken from the Institutional Review Board of Nepal Health Research Council
(Reference number: 1768). The prevalence of osteoporosis was determined, and the associated factors were analyzed using multivariate logistic regression. Dual-Energy X-ray Absorptiometry (GE-Lunar Prodigy) was used to measure Bone Mineral Density (g/cm2) at the proximal femur and lumbar spine. Various factors related to osteoporosis were also analyzed.
Results: There were 384 postmenopausal women and the prevalence of osteoporosis was 82 (21.35%; 95% CI: 17.25%-25.45%)e. The mean age of female with osteoporosis was 67.52±8.84 years and that without osteoporosis was 55.70±7.69 years (p <0.001). The multivariate logistic regression showed aOR 0.82 for body mass index.
Conclusions: The study reports a lower prevalence of osteoporosis than expected in postmenopausal women. There was a significant inverse relationship between osteoporosis and body mass index. However, no significant association was observed between Bone Mineral Density, biochemical variables, smoking, and parity.
Description
Dipendra Pandey
Department of Orthopaedics, Trishuli Hospital, Nuwakot, Nepal
Samina Basnet
Nursing Officer, Trishuli Hospital, Nuwakot, Nepal
Smeena Pradhananga
Department of Obstetrics and Gynecology, Trishuli Hospital, Nuwakot, Nepal
Sarita Shrestha
Department of Internal Medicine, Trishuli Hospital, Nuwakot, Nepal
Badri Rijal
Department of Orthopedics, National Trauma Center, Mahankal, Kathmandu, Nepal
Aman Neupane
Medical Officer, Trishuli Hospital, Nuwakot, Nepal
Utsav Timilsina
Trishuli Hospital, Nuwakot, Nepal
Amit Upreti
Special School for Disabled and Rehabilitation Center, Kathmandu, Nepal
Apil Upreti
National Neuro Center, Kathmandu, Nepal
Rabindra Baskota
Department of Health Services, Kathmandu, Nepal
Pawan Kumar Hamal
Department of Anaesthesiology, Trishuli Hospital, Nuwakot, Nepal