Publication:
Prevalence of Valvular and Non-valvular Atrial Fibrillation and the Application of Antithrombotic Treatment in a Tertiary Care Hospital

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creativeworkseries.issnJNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X
dc.contributor.authorDhungana, Sahadeb Prasad
dc.contributor.authorGhimire, Rinku
dc.date.accessioned2026-03-24T05:43:54Z
dc.date.available2026-03-24T05:43:54Z
dc.date.issued2020
dc.descriptionSahadeb Prasad Dhungana Cardiology Unit, Department of Internal Medicine, Nobel Medical College Teaching Hospital, Biratagar, Nepal https://orcid.org/0000-0003-3071-8710 Rinku Ghimire Department of Pharmacology, Nobel Medical College Teaching Hospital, Biratagar, Nepal
dc.description.abstractAbstract: Introduction: Atrial fibrillation is a common atrial tachyarrhythmia with an increased risk of thromboembolism. This study aims to provide information about the application of antithrombotic treatment based on risk stratification schemes for stroke in real-life clinical practices. Methods: This was a descriptive cross-sectional study in 260 patients admitted at the tertiary care hospital with a diagnosis of atrial fibrillation from January 2019 to February 2020 after approval from the Institutional Review Committee (ref. no. 207/2018). Convenient sampling was used. Predisposing conditions for atrial fibrillation, risk factors for stroke, and the use of antithrombotics were obtained based on the pre-structured questionnaires. Data were analyzed by Statistical Package for the Social Sciences version 20. Results: The prevalence of valvular and non-valvular atrial fibrillation was 125 (48.0%), and 135 (51.9%) respectively. Among patients with a non-valvular variant, 102 (75.5%) had a CHA2DS2VASC score of ≥ 2 who were eligible for oral anticoagulants, 13 (9.6 %) patients received it with a majority having sub-therapeutic international normalized ratio. Among patients with valvular type, only 47 (37.6%) patients were receiving oral anticoagulants and 20 (42.5%) patients achieved therapeutic international normalized ratio. Two hundred forty three (93.4%) patients had dilated left atrium (≥40mm), 119 (45.9%) had hypertension and 27 (10.3%) had diabetes mellitus. Conclusions: Antithrombotics were markedly underused in patients with atrial fibrillation. There is a need for proper application of risk stratification schemes for stroke and appropriate use of antithrombotics to prevent thromboembolism.
dc.identifierhttps://doi.org/10.31729/jnma.5113
dc.identifier.urihttps://hdl.handle.net/20.500.14572/5378
dc.language.isoen_US
dc.publisherNepal Medical Association
dc.subjectanticoagulants
dc.subjectatrial fibrillation
dc.subjectrisk assessment
dc.subjectstroke
dc.titlePrevalence of Valvular and Non-valvular Atrial Fibrillation and the Application of Antithrombotic Treatment in a Tertiary Care Hospital
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage855
oaire.citation.startPage851
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relation.isJournalOfPublicatione6e146a0-0ece-4aba-aa0a-6ccfbd10a12a

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