Publication: Incidence of Contrast Induced Acute Kidney Injury, Its Risk Factors and In-Hospital Outcomes in Patients Undergoing Coronary Angiography and Angioplasty
| creativeworkseries.issn | ISSN (Print) : 1993-2979 | ISSN (Online) : 1993-2987 | |
| dc.contributor.author | Upadhaya, Prashun | |
| dc.contributor.author | Thapa, Pradeep | |
| dc.contributor.author | Gajurel, Ratna M | |
| dc.contributor.author | Sigdel, Mahesh R | |
| dc.date.accessioned | 2026-04-02T06:56:48Z | |
| dc.date.available | 2026-04-02T06:56:48Z | |
| dc.date.issued | 2020 | |
| dc.description.abstract | ABSTRACT Introduction: Contrast-induced acute kidney injury (CI-AKI) is a serious complication of angiographic procedures with significant morbidity and mortality. We aimed to find the incidence, risk factors and outcomes of CI-AKI in patients who have undergone coronary angiography/angioplasty in a referral hospital in Nepal. Methods: It was a descriptive observational study of consenting consecutive patients above 18 years undergoing coronary angiography/angioplasty at Manmohan Cardiothoracic Vascular and Transplant Centre, Nepal from July 2015 to September 2017. CI AKI was defined as an elevation of serum creatinine of >25% or ≥0.5 mg/dl (44 μmol/L) from baseline within 48 hour of exposure to contrast. Statistical analysis was performed using SPSS 18 software. Statistical analysis was completed using Student’s t-test, chi-square test and multivariable logistic regression analysis. Results: Out of 240 patients, 156 (65%) were male, mean age was 60.36±11.29 years. Eighteen patients (7.5%) developed CI-AKI. Incidence of CI-AKI was 20% in patients with chronic kidney disease (CKD), 5.4% in diabetics, 13.6% in patients >70 years, 12.79 % in patients with anaemia and 12.3% in patients with prior contrast exposure. Multivariate logistic regression analysis found smoking and history of prior contrast exposure to be independent predictors for development of CI-AKI. Among patients with CI-AKI, one (5.88%) required dialysis and one (5.88%) died. Conclusion: Incidence of CI-AKI after coronary angiography/angioplasty was 7.5%. Patients with prior contrast exposure and smoking were at significantly increased risk of CI-AKI; higher trend of CI-AKI was seen in patients with CKD, diabetes, elderly and anaemia. Keywords: Angiography, angioplasty, contrast induce acute kidney injury, contrast media,, contrast nephropathy | |
| dc.identifier | https://doi.org/10.59779/jiomnepal.1113 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/5576 | |
| dc.language.iso | en_US | |
| dc.publisher | Institute of Medicine | |
| dc.subject | Angiography | |
| dc.subject | angioplasty | |
| dc.subject | contrast induce acute kidney injury | |
| dc.subject | contrast media | |
| dc.subject | contrast nephropathy | |
| dc.title | Incidence of Contrast Induced Acute Kidney Injury, Its Risk Factors and In-Hospital Outcomes in Patients Undergoing Coronary Angiography and Angioplasty | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 63 | |
| oaire.citation.startPage | 59 | |
| relation.isJournalIssueOfPublication | 6dcbf166-09e2-415e-9156-dc13340873fb | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 6dcbf166-09e2-415e-9156-dc13340873fb | |
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