Publication: Microinvasion: A Clinical Dilemma
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Microinvasive oral squamous cell carcinoma (MIOSCC) is an early stage malignant
tumour,showing invasion of the epithelial cells confined to the superficial lamina
propria. This is matter of debate in respect to the clinical presentation, metastasis,
therapeutic intervention and prognosis.
A 32-year female reported to the department with chief complaint of wound
and burning sensation in her left back region of lower gums. Clinical diagnosis of
erosive oral lichen planus was made and topical steroid was started. The lesion
clinically healed with the use of topical medicine. After stopping the medication the
lesion recurred, following which, excisional biopsy was done. On histopathological
evaluation diagnosis of microinvasive oral squamous cell carcinoma was made.
Recurrence of similar symptom in the same site was seen 10 weeks later, which
now showed features of moderate dysplasia.
Clinical features of microinvasive oral squamous cell carcinoma resembles
premalignant lesion, leading to difficulty in diagnosis, treatment and prognostic
assessment. Thus, adequate representation of this entity is necessary.
KEY WORDS
Microinvasive oral squamous cell carcinoma, Oral lichen planus, Oral potentially
malignant disorder
Description
Regmee P,1 Rimal J,1 Maharjan IK,1 Shrestha A,2 Niroula D,1 Luitel A,1 Chaudhary SK3
1Department of Oral Medicine and Radiology,
2Department of Oral Pathology,
3Department of Periodontology and Oral Implantology,
College of Dental Surgery,
BP Koirala Institute of Health Sciences, Dharan, Nepal.
Keywords
Microinvasive oral squamous cell carcinoma, Oral lichen planus, Oral potentially malignant disorder