Study on Clinico-Laboratory Profile of Children with Scrub Typhus

Jain, N; Jain, V

Publication:
Study on Clinico-Laboratory Profile of Children with Scrub Typhus

creativeworkseries.issn	ISSN 1990-7974 eISSN 1990-7982
dc.contributor.author	Jain, N
dc.contributor.author	Jain, V
dc.date.accessioned	2026-05-27T07:49:11Z
dc.date.available	2026-05-27T07:49:11Z
dc.date.issued	2012
dc.description	N Jain Department of Paediatrics, Himalayan Institute of Medical Sciences and Research Hospital, Dehradun, Uttarakhand V Jain Department of Paediatrics, Himalayan Institute of Medical Sciences and Research Hospital, Dehradun, Uttarakhand
dc.description.abstract	Abstract: Scrub typhus is an acute, febrile, infectious illness caused by Orientia (formerly Rickettsia) tsutsugamushi,an obligate intracellular gram-negative bacterium. Humans are accidental hosts in this zoonotic disease.The present retrospective study describes clinical profile of the children hospitalized in hospital with Scrub Typhus infection during period 2010-2011. 19 hospitalized children with clinical features suggestive of Rickettsial disease (fever, generalized rash) who tested ELISA positive for IgM against Scrub Typhus were included in the present study between the age of 1 years and 15 years. All children presented with fever (100%). 42.10% had lymphadenopathy, 47.36% had eschar and 57.89% patients had cough. 26.31, 21.05%, 10.52%, had hepatomegaly, pain abdomen, and respiratory distress and gastrointestinal bleed respectively. All of the children were investigated and treated with as per protocol. None of them died. We think that Rickettsial infection is not quite common in this region but study showed that it is not an uncommon entity and thus, high degree of suspicion, knowledge of geographical distribution and clinical features of Rickettsial disease helps in its early diagnosis and treatment.
dc.identifier	https://doi.org/10.3126/jnps.v32i2.5683
dc.identifier.uri	https://hdl.handle.net/20.500.14572/6272
dc.language.iso	en_US
dc.publisher	Nepal Paediatric Society (JNPS)
dc.subject	Rickettsial
dc.subject	Scrub Typhus
dc.subject	Orientia Tsutsugamushi
dc.title	Study on Clinico-Laboratory Profile of Children with Scrub Typhus
dc.type	Article
dspace.entity.type	Publication
local.article.type	Case Series
oaire.citation.endPage	192
oaire.citation.startPage	187
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