Publication: Microbial Resistance Caused by Antibiotic Prophylaxis with Amoxicillin in a Male Infant with Vesicoureteral Reflux
Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
Vesicoureteral reflux is a common condition in infants with urinary tract infection. Although antibiotic prophylaxis to prevent recurrent urinary tract infection is widely performed, its effectiveness remains controversial. Herein we report a seven- month-old boy with vesicoureteral reflux. Antibiotic prophylaxis with amoxicillin caused microbial resistance accompanied by recurrent urinary tract infection. Subsequent antibiotic prophylaxis with sulfamethoxazole-trimethoprim was effective until spontaneous remission of vesicoureteral reflux occurred. Sulfamethoxazole-trimethoprim, but not amoxicillin, should be considered as an agent for antibiotic prophylaxis in infants with vesicoureteral reflux.
Description
Kazuto Taniguchi
Tara Town Hospital, Tara, Japan
Sakumo Kii
Tara Town Hospital, Tara, Japan
Masafumi Oka
Department of Paediatrics, Ureshino Medical Centre, Ureshino, Japan
Kazuyasu Uemichi
Tara Town Hospital, Tara, Japan
Keywords
antibiotic prophylaxis, microbial resistance, vesicoureteral reflux