Publication:
Clinical and Pathological Features of Primary Cutaneous Lymphomas in Nepal: A retrospective cohort study from a dermatology referral centre

creativeworkseries.issn1812-2027
dc.contributor.authorPaudel, U
dc.contributor.authorParajuli, S
dc.date.accessioned2026-01-09T06:08:55Z
dc.date.available2026-01-09T06:08:55Z
dc.date.issued2024
dc.descriptionPaudel U, Parajuli S Department of Dermatology and Venereology Maharajgunj Medical Campus Institute of Medicine, Tribhuvan University Maharajgunj, Kathmandu, Nepal
dc.description.abstractABSTRACT Background Primary cutaneous lymphomas (PCLs) are rare diagnoses in Nepal and are not well characterized till date. Objective To evaluate clinical and pathological features of Primary cutaneous lymphomas in Nepal. Method We retrospectively reviewed outpatient and inpatient records of a dermatology referral centre of Kathmandu, Nepal for clinical and pathological findings of cases diagnosed as cutaneous lymphomas from July 2010 through July 2020. The final diagnosis was made based on 2008 World Health Organization classification and its update 2018. Result There were 12 cases of Primary cutaneous lymphomas diagnosed during this period. The age of presentation ranged from 19 years to 81 years (Mean: 53.4 years ± 21.5 years, SD). There were ten cases of cutaneous T-cell lymphoma (CTCLs) and two cases of cutaneous B- cell lymphomas (CBCLs). Among cutaneous T-cell lymphoma, there were four cases of primary cutaneous anaplastic large- cell Lymphoma (PCALCL), two cases of classic (patch/plaque) mycosis fungoides (MF), two cases of folliculotropic mycosis fungoides (FMF), and one case each of primary cutaneous aggressive epidermotropicCD8+ T-cell lymphoma and lymphomatoid papulosis. Among cutaneous B- cell lymphomas, there was one case of primary cutaneous marginal zone B- cell lymphoma, and one case of primary cutaneous follicle centre lymphoma. Most cases of MF presented at stage IB (75%), and three patients of primary cutaneous lymphomas died during this period. Conclusion Primary cutaneous lymphomas appear to be very rare in this study and presentations ranged from classic Mycoses Fungoides to aggressive T-cell lymphomas. Cutaneous T-cell lymphomas appeared to be more common than cutaneous B- cell lymphomas in this study. KEY WORDS Anaplastic, B-cell, Cutaneous, Lymphoma, T-Cell
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4160
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectAnaplastic
dc.subjectB-cell
dc.subjectCutaneous
dc.subjectLymphoma
dc.subjectT-Cell
dc.titleClinical and Pathological Features of Primary Cutaneous Lymphomas in Nepal: A retrospective cohort study from a dermatology referral centre
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage159
oaire.citation.startPage154
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relation.isJournalIssueOfPublication.latestForDiscovery0ac6b1c4-56bd-40d8-9827-11dcbc56b419
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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