Publication: Gallbladder Volume in Sikkimese Population
Date
2016
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Gall bladder volume can have clinical and therapeutic implications and possibly affect
certain pathophysiological mechanisms of many diseases affecting the gallbladder
including gall stones.
Objective
The objective of the study was to establish baseline indices of gallbladder volume
for the Sikkimese population and determine its correlation with age, sex and Body
Mass Index.
Method
A prospective epidemiologic study on selected 100 patients (equal male to female
ratio) over the age of 36 years, undergoing ultrasound scan of abdomen, was
undertaken. Age, sex, Body Mass Index and gall bladder volume for each subject
were collected and analysed statistically. Spearman’s correlation test was performed
to look for significant variables.
Result
The overall mean gallbladder volume in the present study was 15.47±7.9 ml
with 17.2±8.9 ml and 13.74±6.4 ml being average volumes in males and females
respectively, which gives the baseline indices for the Sikkimese population. Gall
bladder volume was strikingly increased in obese subjects. There was a positive
correlation between gall bladder volume and age (r=0.114), gender (r=0.182)
and BMI (r= 0.175) but the strength of correlation was weak and not statistically
significant (p <0.001).
Conclusion
Ultrasonography is an easy and effective method for evaluation of gall bladder
volume. Sikkimese males have a larger fasting gall bladder volume which is directly
correlated with higher body mass index. Fasting gall bladder volume has a weak
correlation with advancing age.
KEY WORDS
Age, body mass index, gall bladder, ultrasonography
Description
Dey R,1 Sharma BK,2 Singh VK,3 Jha DK,1
1Department of Physiology
2Department of Radiodiagnosis
3Department of Surgery
Sikkim Manipal Institute of Medical Sciences(SMIMS)
Sikkim Manipal University,5th Mile, Tadong, Gangtok,
Sikkim. 737102 India
Keywords
Age, Body mass index, Gall bladder, Ultrasonography