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Prediction of Postoperative Major Complications in Pancreaticoduodenectomy -a Prospective Comparative Analysis of Braga and WHipple-ABACUS Scores

creativeworkseries.issn1812-2027
dc.contributor.authorSah, DN
dc.contributor.authorLakhey, PJ
dc.contributor.authorBhandari, RS
dc.date.accessioned2026-01-05T06:35:33Z
dc.date.available2026-01-05T06:35:33Z
dc.date.issued2023
dc.descriptionSah DN,1 Lakhey PJ,2 Bhandari RS2 1Department of General Surgery Birat Medical College Teaching Hospital Biratnagar, Morang, Nepal 2Department of Surgical Gastroenterology Tribhuvan University Teaching Hospital Maharajgunj, Kathmandu, Nepal
dc.description.abstractABSTRACT Background Major complications following pancreaticoduodenectomy have a severely deleterious effect on postoperative course, rather than just occurrence of pancreatic fistula. Surgical risk stratification with Braga and WHipple-ABACUS have been proposed and validated. Objective The study aimed at comparing the Braga and WHipple-ABACUS scores for prediction of major complications following pancreaticoduodenectomies. Method This was a prospective observational study at the Tribhuvan University Teaching Hospital from February 2018 to April 2019. After ethical approval, all consecutive 41 patients who underwent pancreaticoduodenectomies were included. Each patient was graded in Braga and WHipple-ABACUS scores. Perioperative events occurring over 30 days were graded as per Clavien -Dindo complications for pancreatic surgery. The predictive value of the scores were assessed using a receiver operating characteristic curve analysis. The categorical data were compared using the Pearson χ2 test or Fisher’s exact test. Result Over period of 14 months, total of 41 patients (M:F=2.15:1) with median age of 58 years (range, 21-86) underwent pancreatoduodenectomy. The mean scores were Braga (4.6±3.1) and WHipple-ABACUS (1.8±1.6). Major complications over 30 days were developed in 11 patients with five mortality. There were significant differences in mean values of Braga score (7.0±3.4 vs 3.7±2.6, p-value=0.02) and WHipple- ABACUS score (3.2±1.8 vs 1.3±1.3, p-value=0.01) in patients with major complications to those without respectively. The area under curves for Braga and WHipple-ABACUS scores were 0.800 and 0.779 respectively. Conclusion Both WHipple-ABACUS and Braga scores are easy to calculate and predict the development of major complications significantly in patients undergoing pancreatoduodenectomy. KEY WORDS Braga score, Pancreaticoduodenectomy, Post-operative pancreatic fistula, WHipple- ABACUS score
dc.identifier.urihttps://hdl.handle.net/20.500.14572/4036
dc.language.isoen_US
dc.publisherKathmandu University
dc.subjectBraga score
dc.subjectPancreaticoduodenectomy
dc.subjectPost-operative pancreatic fistula
dc.subjectWHipple- ABACUS score
dc.titlePrediction of Postoperative Major Complications in Pancreaticoduodenectomy -a Prospective Comparative Analysis of Braga and WHipple-ABACUS Scores
dc.typeArticle
dspace.entity.typePublication
local.article.typeOriginal Article
oaire.citation.endPage132
oaire.citation.startPage125
relation.isJournalIssueOfPublication7b2d2fc6-baf4-41c0-ae80-a84bd514fa43
relation.isJournalIssueOfPublication.latestForDiscovery7b2d2fc6-baf4-41c0-ae80-a84bd514fa43
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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