Publication: Positive Thyroid Peroxidase Antibody among Women with Polycystic Ovarian Syndrome Visiting an Infertility Clinic at a Tertiary Care Centre
| creativeworkseries.issn | JNMA Print ISSN: 0028-2715; Online ISSN: 1815-672X | |
| dc.contributor.author | Sharma, Vijay Kumar | |
| dc.contributor.author | Baidya, Sujata | |
| dc.contributor.author | Kandel, Pratibha | |
| dc.contributor.author | Rajkarnikar, Smrity | |
| dc.contributor.author | Niraula, Apeksha | |
| dc.contributor.author | Dubey, Raju Kumar | |
| dc.contributor.author | Raut, Mithileshwer | |
| dc.contributor.author | Bhattarai, Aseem | |
| dc.contributor.author | Tuladhar, Eans Tara | |
| dc.contributor.author | Koirala, Poonam | |
| dc.date.accessioned | 2025-08-21T04:38:15Z | |
| dc.date.available | 2025-08-21T04:38:15Z | |
| dc.date.issued | 2023 | |
| dc.description | Vijay Kumar Sharma Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Sujata Baidya Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Pratibha Kandel Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Smrity Rajkarnikar Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Apeksha Niraula Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Raju Kumar Dubey Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Mithileshwer Raut Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Aseem Bhattarai Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Eans Tara Tuladhar Department of Clinical Biochemistry, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal Poonam Koirala Department of Obstetrics and Gynaecology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal | |
| dc.description.abstract | Abstract Introduction: Polycystic ovarian syndrome is the most common endocrine-metabolic disorder, affecting women of reproductive age groups, which shares various symptoms with thyroid dysfunctions. Despite it predisposition of aforesaid cohorts to autoimmunity, these etiologies have not adequately been studied in them. This study aimed to find out the prevalence of positive thyroid peroxidase antibodies among women with polycystic ovarian syndrome visiting an infertility clinic at a tertiary care centre. Methods: This was a cross-sectional study conducted at a tertiary care centre among patients visiting the infertility clinic at the Department of Obstetrics and Gynaecology from 21 September 2022 to 21 February 2023. Biochemical analysis of thyroid hormones, gonadal hormones, anti-mullerian hormone and thyroid peroxidase antibody were done in Abbott ARCHITECT ci4100 and SNIBE Maglumi 800 autoanalyzer. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval. Results: Among 70 participants, thyroid peroxidase antibody was positive in 16 (22.86%) (13.02-32.69, 95% Confidence Interval). The mean age of the patients was 28.25±5.26 years. In the individuals with thyroid-stimulating hormone below 2.5 mIU/l, 5 (31.25%) had positive thyroid peroxidase antibody titre. Conclusions: The prevalence of positive thyroid peroxidase antibodies among women with polycystic ovarian syndrome is similar to other studies done in similar settings. Regular monitoring of thyroid peroxidase antibodies is recommended in these women to guide conception in order to evade inevitable adverse pregnancy outcomes. | |
| dc.identifier | https://doi.org/10.31729/jnma.8366 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14572/1835 | |
| dc.language.iso | en_US | |
| dc.publisher | Nepal Medical Association | |
| dc.title | Positive Thyroid Peroxidase Antibody among Women with Polycystic Ovarian Syndrome Visiting an Infertility Clinic at a Tertiary Care Centre | |
| dc.type | Article | |
| dspace.entity.type | Publication | |
| local.article.type | Original Article | |
| oaire.citation.endPage | 944 | |
| oaire.citation.startPage | 941 | |
| relation.isJournalIssueOfPublication | 90e36b9c-9b2b-48a5-989f-d2fc206187ed | |
| relation.isJournalIssueOfPublication.latestForDiscovery | 90e36b9c-9b2b-48a5-989f-d2fc206187ed | |
| relation.isJournalOfPublication | e6e146a0-0ece-4aba-aa0a-6ccfbd10a12a |