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Lues Maligna in Immunocompetent Individuals: Two Case Reports

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creativeworkseries.issnISSN 2091-0231 eISSN 2091-167X
dc.contributor.authorAdhikari, Bishnu Prasad
dc.contributor.authorBasnet, Binamra
dc.contributor.authorNeupane, Bidhan
dc.contributor.authorKumar, Ajay
dc.contributor.authorSapkota, Surendra
dc.contributor.authorJoshi, Mandeep Dutta
dc.contributor.authorSubedi, Kamala
dc.date.accessioned2025-10-10T08:53:31Z
dc.date.available2025-10-10T08:53:31Z
dc.date.issued2025
dc.descriptionAuthor Biographies Bishnu Prasad Adhikari Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal. Binamra Basnet, Manipal College of Medical Sciences, Pokhara, Nepal Assistant Professor,Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Bidhan Neupane, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Ajay Kumar, Manipal College of Medical Sciences, Pokhara, Nepal Professor, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Surendra Sapkota, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Mandeep Dutta Joshi, Manipal College of Medical Sciences, Pokhara, Nepal Junior Resident, Department of Dermatology, Manipal College of Medical Sciences, Pokhara, Nepal Kamala Subedi, Pokhara Academy of Health Sciences, Ramghat, Pokhara, Nepal Assistant Professor, Department of Microbiology, Pokhara Academy of Health Sciences, Ramghat, Pokhara, Nepal
dc.description.abstractAbstract: Lues maligna, also termed malignant syphilis or rupioid syphilis, is a rare and severe form of secondary syphilis. Clinically, the condition is characterized by unusual nodules and necrotic and ulcerated skin lesions covered by thick, lamellated crusts associated with severe constitutional symptoms. Most of the lues maligna cases have been observed in immunocompromised individuals, including Human Immunodeficiency Virus (HIV) co-infected patients, alcoholics, malnourished individuals, and patients with debilitating illnesses. However, immunocompetent individuals can also develop this form of illness. Herein, we present 2 cases of lues maligna in immunocompetent patients. The first case is a 38-year-old immunocompetent married female, while the second case is a 34-old married male, both presenting with multiple diffuse noduloulcerative lesions with rupioid crusts. Serological tests for syphilis were positive in both patients and a biopsy of both patients showed forms consistent with secondary syphilis.
dc.identifierhttps://doi.org/10.3126/njdvl.v23i1.74403
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2564
dc.language.isoen_US
dc.publisherSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
dc.subjectFisher's criteria
dc.subjectHuman immunodeficiency virus
dc.subjectMalignant syphilis
dc.subjectRupioid syphilis
dc.subjectUlceronodular-rupioid syphilis
dc.titleLues Maligna in Immunocompetent Individuals: Two Case Reports
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage54
oaire.citation.startPage51
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relation.isJournalIssueOfPublication.latestForDiscoverye8242928-66a2-470a-8f53-47365c4dd836
relation.isJournalOfPublicationb2ab7aab-75b0-4bd1-9ed0-b8a91c68201a

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