Publication: Burden of Stroke in Nepal: Findings from Global Burden of Disease Dataset 2017
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Stroke is the second leading cause of death and disability worldwide including Asian
countries, surpassing ischemic heart disease. Stroke accounts for 10% of global
death, of which more than three fourth occur in low- and middle-income countries.
An exact estimate of the burden of stroke in Nepal is not available.
Objective
To assess the burden of stroke including disability and death over time in Nepal and
compare it with other South Asian countries.
Method
We retrieved data from the Institute of Health Metrics and Evaluation’s Global
Burden of Diseases database of 2017 on stroke deaths, disability-adjusted life years,
incidence, and prevalence rates, for both genders from Nepal, Bangladesh, Pakistan,
Bhutan, and India by year. We assessed the trend of deaths and Disability-Adjusted
Life Years (DALYs) due to stroke from 1990 to 2017; and the contribution of major risk
factors to stroke burden in 2017.
Result
Stroke contributed 7.6% of total deaths and 3.5% of total DALYs in Nepal, with a
higher burden among the male and old age population. Intracerebral hemorrhage
was the dominant type of stroke in Nepal with the highest proportion of deaths and
DALYs. Among the South Asian countries, incidence, prevalence, and burden of stroke
were highest in Bangladesh. Intracerebral hemorrhage contributed the highest DALYs
in South Asian countries. High systolic blood pressure was contributing the maximum
DALYs due to stroke in Nepal.
Conclusion
Hemorrhagic stroke causes high mortality and DALYs in Nepal. Most of the burden of
stroke is attributed to high blood pressure in Nepal.
KEY WORDS
Global burden of disease (GBD), Nepal, Prevalence, Risk factor, Stroke
Description
Pyakurel M,1,2 Bhattarai S,3 Joshi B,4,5 Koju RP,6,7 Shrestha A,3,8-10
1Inclusive Partnership Against Violence (InPAV)
Project, Green Tara Nepal, Baluwatar, Nepal. 2Fellow,
CVD Translational Research Program, Kathmandu
University School of Medical Sciences, Dhulikhel,
Kavre, Nepal. 3Department of Community Programs,
Dhulikhel Hospital Kathmandu University Hospital,
Dhulikhel, Kavre, Nepal. 4University of Bordeaux,
Inserm, Research Institute for development
(IRD), France. 5Center for Research Innovation
and Development (CRID), Lalitpur, Nepal. 6Dean,
Kathmandu University School of Medical Sciences,
Dhulikhel, Kavre. 7Department of Internal Medicine,
Dhulikhel Hospital, Kathmandu University Hospital,
Dhulikhel, Kavre. 8Department of Public Health,
Kathmandu University School of Medical Sciences,
Dhulikhel, Kavre, Nepal. 9Department of Chronic
Disease Epidemiology, Yale School of Public Health,
New Haven, USA. 10Institute for Implementation
Science and Health, Kathmandu, Nepal.
Keywords
Global burden of disease (GBD), Nepal, Prevalence, Risk factor, Stroke