Publication: Ovarian Tumors: Pattern of Histomorphological Types- A 10 Years Study in a Tertiary Referral Center and Review of Literature
Date
2016
Journal Title
Journal ISSN
Volume Title
Publisher
Kathmandu University
Abstract
ABSTRACT
Background
Ovarian cancer accounts for 6% of all cancers in females. Among cancers of female
genital tract, the incidence of ovarian cancers ranks below only carcinoma of the
cervix and the endometrium.
Objective
To find the frequency of different types of histomorphological types and their
association with age, side and size distribution.
Method
This study is a hospital based retrospective study carried out in the Department of
Pathology, Manipal Teaching Hospital over a time period from Jan. 2006 to Sep. 2015.
Specimens were received from the Manipal Teaching Hospital and other hospitals
within the Himalayan valley of Pokhara. All the clinical and histolpathological data
were retrieved from the departmental data bank and were analyzed.
Result
A total of 409 cases of ovarian tumors have been reported in the same period. Among
them, 215 cases were of surface epithelial origin including 172 benign, 07 borderline
and 36 malignant cases. Among the surface epithelial tumors, the commonest was
serous cystadenoma (119 cases) followed by mucinous cyst adenoma (40 cases).
There were 176 cases of tumors with germ cell origin which included 170 cases of
teratoma, four dysgerminoma and one each case of choriocarcinoma and yolk sac
tumor. Among seven metastatic tumors, one case was of Krukenberg tumor. Age
range was 12 to 90 years and the size range from 3 to 36 cm.
Conclusion
In our study, we analyzed all the spectrum of ovarian tumors diagnosed on
morphological bases and most of the findings were similar to other national &
international studies. However, we have reported increased percentage of mucinous
tumors and less sex cord stromal tumors.
KEY WORDS
Germ cell tumor, metastatic, mucinous, ovarian tumor, serous
Description
Ghosh A,1 Ghartimagar D,1 Thapa S,1 Sathian B,2 Narasimhan R,1 Talwar OP1
1Department of Pathology
2Department of Community Medicine
Manipal Teaching Hospital
Manipal College of Medical Science
Pokhara, Nepal
Keywords
Germ cell tumor, Metastatic, Mucinous, Ovarian tumor, Serous