Publication: Methotrexate as a Suspected Trigger of Macrophage Activation Syndrome in Juvenile Idiopathic Arthritis
Date
2017
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Nepal Paediatric Society (JNPS)
Abstract
Abstract:
A four year old girl with systemic onset juvenile idiopathic arthritis (SOJIA) developed macrophage activation syndrome (MAS) shortly after starting methotrexate. We observed methotrexate is a likely trigger of MAS in SOJIA. Possibly, there are only two case reports suggesting methotrexate triggered MAS. We reviewed the literature for possible mechanisms.
Description
Soumya Roy
Institute Of Child Health, Kolkata
Subroto Chakrabartty
Institute Of Child Health, Kolkata
Keywords
Macrophage activation syndrome, Methotrexate, Systemic Onset Juvenile Idiopathic Arthritis