Publication:
Clinical Practice Recurrent Severe Obscure Gastro Intestinal- Bleeding in a 20 Year Old Man

creativeworkseries.issn1812-2027
dc.contributor.authorBreidert, M
dc.contributor.authorMandal, A
dc.contributor.authorKoller, A
dc.contributor.authorHuellebrand, N
dc.contributor.authorMalla, B
dc.date.accessioned2025-08-27T06:48:42Z
dc.date.available2025-08-27T06:48:42Z
dc.date.issued2013
dc.descriptionBreidert M,1 Mandal A,2 Koller A,3 Huellebrand N,3 Malla B,4 Department of Internal Medicine 1District Hospital Clinic Altmühltal Germany, Teaching Hospital of the Technical University Munich, Germany 2Dhulikhel Hospital- Kathmandu University Hospital Teaching Hospital of the University of Kathmandu Nepal 3Department of Visceral Surgery District Hospital Clinic Altmühltal, Germany, Teaching Hospital of the Technical University Munich, Germany 4Department of Surgery Dhulikhel Hospital- Kathmandu University Hospital Teaching Hospital of the University of Kathmandu Nepal
dc.description.abstractABSTRACT Morbus Osler-Weber-Rendu syndrome also known as Hereditary hemorrhagic telangiectasia (HHT) and Meckel’s diverticulum is a rare combination disorder. Our case presented with the recurrent obscure gastrointestinal (GI) bleeding for several years. He came with a massive active lower gastrointestinal bleeding. Ultimatively, he underwent an exploratory laparotomy along with intraoperative colonoscopy. A Meckel’s diverticulum in combination with multiple erosions was found as a probable cause of the massive gastrointestinal bleeding. An ileo-caeacal resection had been performed and by the pathologist multiple telangiectasias in the resected ileum were established. Blood was sent for genetics and was negative for ENG, ALK-1, and SMAD-4 genes. The patient was discharged after 10 days from time of admission and is under regular follow up without any further bleeding. In this case, despite sophisticated techniques for investigations the cause of the GI-bleeding with several esophagogastroduodenoscopies and colonoscopies, mesenteric angiography and finally an oral double balloon enteroscopy was misdiagnosed till the intra operative endoscopy showed a middle GI-bleeding. The management for obscure GI-bleeding is discussed for countries with lower medical facilities like Nepal in our case with Morbus Osler-Weber-Rendu syndrome. KEY WORDS Meckel`s diverticulum, middle gastrointestinal bleeding, morbus osler-weber-rendu
dc.identifier.urihttps://hdl.handle.net/20.500.14572/2116
dc.language.isoen_US
dc.publisherKathmandu Unversity
dc.titleClinical Practice Recurrent Severe Obscure Gastro Intestinal- Bleeding in a 20 Year Old Man
dc.typeArticle
dspace.entity.typePublication
local.article.typeCase Report
oaire.citation.endPage85
oaire.citation.startPage81
relation.isJournalIssueOfPublication3497e646-4a14-4040-b03d-e45b0beebdb8
relation.isJournalIssueOfPublication.latestForDiscovery3497e646-4a14-4040-b03d-e45b0beebdb8
relation.isJournalOfPublicationa782b7ff-cf89-4178-ad1c-11ed89cfe1bd

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