Publication: Common pathogens isolated in diabetic foot infection in Bir Hospital
Date
2006
Authors
Journal Title
Journal ISSN
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Publisher
Kathmandu University
Abstract
Aim: Foot ulcers are a frequent complication of patients suffering with diabetes mellitus, accounting for up to 20%
of diabetes-related hospital admission6. Secondary infection of these ulcers is by far the leading cause of amputation
of feet and legs and the polymicrobial nature of diabetic foot infection has been well documented in the literature.
The present study sought to reveal the bacterial etiology of diabetic foot ulcer in patients presenting to Bir Hospital.
Method: A 1 year retrospective study was carried out to analyse the bacterial isolates of all patients admitted with
diabetic foot infection presented with Wagner grade 2 -5 ulcers. Bacteriological diagnosis and antibiotic sensitivity
profiles were carried out and analysed using standard procedures.
Results: Diabetic polyneuropathy was found to be common in (51.1%) and gram positive bacteria were isolated
more often than gram-negative ones in the patients screened. The most frequent bacterial isolate were
Staphylococcus aureus (38.4%), Pseudomonas aeruginosa (17.5%), and Proteus (14%). Imipenem was the most
effective agent against gram-negative organisms. Vancomycine was found to be most effective against gram-
positive organisms. 13
Conclusion: Staph aureus and Pseodomonas aeruginosa were the most common causes of diabetic foot infections in
Bir Hospital. Theses wounds require use of combined antimicrobial therapy for initial management, repeated
dressing and wound debridements were done.
Description
Sharma VK 1, Khadka PB2, Joshi A 3
, Sharma R 4
1Professor of Surgery, 2
MS (Ortho), 3Resident, MS (Ortho), 4
Intern, General Surgery Unit III, Bir Hospital NAMS